Results 61 to 70 of about 987,756 (247)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The effect of external forces on discrete motion within holographic optical tweezers [PDF]

open access: yes, 2007
Holographic optical tweezers is a widely used technique to manipulate the individual positions of optically trapped micron-sized particles in a sample.
Eriksson, E.   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Geôle, enjôler, enjoliver : surveiller et (p)unir dans Lolita

open access: yesSillages Critiques, 2010
Nabokov writes in “On a book entitled Lolita” that the “initial shiver of inspiration” that triggered the composition of the novel was prompted by a newspaper story about an ape in the Jardin des Plantes which had produced a drawing representing the bars
René Alladaye
doaj   +1 more source

Towards surface quantum optics with Bose-Einstein condensates in evanescent waves

open access: yes, 2008
We present a surface trap which allows for studying the coherent interaction of ultracold atoms with evanescent waves. The trap combines a magnetic Joffe trap with a repulsive evanescent dipole potential.
A. Aspect   +27 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Monitoring Mosquito Abundance: Comparing an Optical Sensor with a Trapping Method

open access: yesInsects
Optical sensors have shown significant promise in offering additional data to track insect populations. This article presents a comparative study between abundance measurements obtained from a novel near-infrared optical sensor and physical traps.
Topu Saha   +4 more
doaj   +1 more source

Two novel flight-interception trap designs for low-cost forest insect surveys [PDF]

open access: yes, 2014
This paper introduces two passive trap designs for the survey of flying Coleoptera and other insects which can be constructed on very low budgets at < £1 per trap.
Blake, Shona   +4 more
core  

Operation of a Microfabricated Planar Ion-Trap for Studies of a Yb$^+$-Rb Hybrid Quantum System

open access: yes, 2019
In order to study interactions of atomic ions with ultracold neutral atoms, it is important to have sub-$\mu$m control over positioning ion crystals. Serving for this purpose, we introduce a microfabricated planar ion trap featuring 21 DC electrodes. The
Bahrami, Abasalt   +5 more
core   +1 more source

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