Results 71 to 80 of about 819,963 (347)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Use of Decoy Traps to Protect Blueberries from Juvenile European Starlings

open access: yesHuman-Wildlife Interactions, 2017
Fruit consumption by large flocks of juvenile European starlings (Sturnus vulgaris) is a serious problem for growers of strawberries, grapes, apples, cherries, blueberries, and other small fruit.
Michael R. Conover, Richard A. Dolbeer
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Licensing of Commensal Rodent Trappers

open access: yesEDIS, 2018
The Florida Department of Agriculture and Consumer Services’ Bureau of Licensing and Enforcement (FDACS BLE) administers Limited Certification Categories to certify Governmental or Private applicators.
Frederick M. Fishel
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Unbiased Sampling for Rodents and Other Small Mammals: How to Overcome Neophobia Through Use of an Electronic-Triggered Live Trap—A Preliminary Test

open access: yesFrontiers in Ecology and Evolution, 2019
Live-trapping of urban rodents and other small mammals poses several challenges for researchers and pest control professionals (PMPs). Most traps are novel to the natural environment and elicit neophobic, or trap-shy, behaviors. Thus, animals captured in
Rafal Stryjek   +2 more
doaj   +1 more source

Electric field-dependent dynamic polarizability and "magic" conditions for optical trapping of polar molecules

open access: yes, 2010
Selection of "magic" trapping conditions with ultracold atoms or molecules, where pairs of internal states experience identical trapping potentials, brings substantial benefits to precision measurements and quantum computing schemes.
DeMille, David, Kotochigova, Svetlana
core   +1 more source

Simplification traps [PDF]

open access: yesJournal of Chemical Biology, 2011
When experiments are analyzed with simple functions, one gets simple results. A trap springs when experiments show deviations from the expected simplicity. When kinetic experiments do not follow exponential curves, they simply are not of the first or pseudofirst order. They can and have to be calculated on the base of plausible reaction schemes.
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Practical, effective and safer: Placing traps above ground is an improved capture method for the critically endangered ngwayir (western ringtail possum; Pseudocheirus occidentalis)

open access: yesAnimal Welfare
The capture of wild-living animals can provide valuable information that is critical in developing and implementing effective conservation actions.
Sara Corsetti   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy