Pharmacovigilance‐Based Identification and Mechanistic Exploration of Periodontitis‐Related Drugs
ABSTRACT Background Periodontitis is a common chronic inflammatory disease. However, drug‐related risks and underlying molecular mechanisms remain underexplored from large real‐world data. Methods We first mined the US Food and Drug Administration Adverse Event Reporting System (FAERS) database to identify drugs disproportionately associated with ...
Wuda Huoshen+11 more
wiley +1 more source
Enhanced Anti‐tumor Effect of Trastuzumab in Combination with Cisplatin
Ichiro Naruse+3 more
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Enhancement of the p27Kip1‐mediated antiproliferative effect of trastuzumab (Herceptin) on HER2‐overexpressing tumor cells [PDF]
Radu Marcheş, Jonathan W. Uhr
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ABSTRACT Sleep disturbance is a common symptom experienced by approximately 70% of breast cancer survivors and persists after the conclusion of chemotherapy. This study aimed to quantify the circadian disruption of the core body temperature (CBT) rhythm and its correlation with sleep disturbance following chemotherapy.
Joon Sung Shin+12 more
wiley +1 more source
The Use of Cell Line Standards to Reduce HER-2/neu Assay Variation in Multiple European Cancer Centers and the Potential of Automated Image Analysis to Provide for More Accurate Cut Points for Predicting Clinical Response to Trastuzumab [PDF]
Anthony Rhodes+4 more
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Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer.
S. Swain+13 more
semanticscholar +1 more source
Inhibition of ErbB2 mitigates secondary denervation after traumatic muscle injury
Abstract figure legend Our study evaluated the therapeutic potential of ErbB2 inhibition (Herceptin) after volumetric muscle loss (VML) injury, primarily evaluating improvements at the neuromuscular junctions (NMJ). A full thickness model of VML injury to the tibialis anterior muscle of adult Lewis rats was used, and treatments included Herceptin, a ...
Jacob R. Sorensen+6 more
wiley +1 more source
Clinical Experience with Trastuzumab (Herceptin)
Charles L. Vogel, Sandra Franco
openalex +1 more source