Results 41 to 50 of about 2,143,253 (310)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Significance of Elecsys (R) S100 immunoassay for real-time assessment of traumatic brain damage in multiple trauma patients [PDF]

, 2006
Background: The neuroprotein S100 released into the circulation has been suggested as a reliable marker for primary brain damage. However, safe identification of relevant traumatic brain injury (TBI) may possibly be hampered by S100 release from ...
Alber, Anderson, Anderson, Biberthaler, Biberthaler, Blomquist, Donato, Haimoto, Ingebrigtsen, Jonsson, Kahn, Leffers, Marshall, Mussack, Mussack, Mussack, Mussack, Nast, Otto, Pelinka, Pelinka, Raabe, Rosen, Rothoerl, Sauaia, Savola, Schafer, Shackford, Snyder, Stein, Taylor, Thurman, Townend, Unden, Usui, Woertgen, Woertgen, Wunderlich, Zimmer   +38 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

A Comparison of PTSD, AUD, and MDD Symptom Patterns in Different Trauma Types [PDF]

, 2020
A Comparison of PTSD, AUD, and MDD Symptom Patterns in Different Trauma Types Elizabeth Crump, Depts. of Biology and Sociology, with Dr. Kaitlin Bountress, Virginia Institute of Psychiatric and Behavioral Genetics About 66% of college students have been ...
Crump, Elizabeth
core   +1 more source

Prospective observational study of point-of-care creatinine in trauma. [PDF]

, 2016
Background:Patients with trauma are at risk for renal dysfunction from hypovolemia or urological injury. In austere environments, creatinine values are not available to guide resuscitation. A new portable device, the Stat Sensor Point-of-care (POC) Whole
Carden, Anthony J, Galante, Joseph M, Gross, Eric, Mattice, Jennifer, Salcedo, Edgardo S, Shepard, Jan, Tran, Nam K   +6 more
core   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Fracture Detection in Pediatric Wrist Trauma X-ray Images Using YOLOv8 Algorithm [PDF]

arXiv, 2023
Hospital emergency departments frequently receive lots of bone fracture cases, with pediatric wrist trauma fracture accounting for the majority of them. Before pediatric surgeons perform surgery, they need to ask patients how the fracture occurred and analyze the fracture situation by interpreting X-ray images.
arxiv  

Trauma is danger [PDF]

Journal of Translational Medicine, 2011
Abstract Background Trauma is one of the leading causes of death in young adult patients. Many pre-clinical and clinical studies attempt to investigate the immunological pathways involved, however the true mediators remain to be elucidated.
Nancy Porterfield, Thomas A. Davis, Eric A. Elster, Eric A. Elster, Eric A. Elster, Paul F. Hwang, Paul F. Hwang, Paul F. Hwang, Dylan Pannell   +8 more
openaire   +5 more sources

WSES classification and guidelines for liver trauma [PDF]

, 2016
The severity of liver injuries has been universally classified according to the American Association for the Surgery of Trauma (AAST) grading scale. In determining the optimal treatment strategy, however, the haemodynamic status and associated injuries ...
Abu-Zidan, Fikri M., Ansaloni, Luca, Biffl, Walter, Catena, Fausto, Ceresoli, Marco, Coccolini, Federico, Coimbra, Raul, Fraga, Gustavo, Ivatury, Rao, Kluger, Yoram, Montori, Giulia, Moore, Ernest E., Moore, Frederick A., Naidoo, Noel, Peitzman, Andrew, Rizoli, Sandro, Sartelli, Massimo, Weber, Dieter, Zanini, Nicola   +18 more
core   +2 more sources

VOCSMAT: a connectionist-inspired treatment proposal for relational traumas [PDF]

arXiv, 2017
Psychological traumas are thought to be present in a wide range of conditions, including post-traumatic stress disorder, disorganised attachment, personality disorders, dissociative identity disorder and psychosis. This work presents a new psychotherapy for psychological traumas, based on a functional model of the mind, built with elements borrowed ...
arxiv