Results 51 to 60 of about 2,995,823 (376)

Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

World Psychiatry, 2018
This paper reviews the research evidence concerning the intergenerational transmission of trauma effects and the possible role of epigenetic mechanisms in this transmission. Two broad categories of epigenetically mediated effects are highlighted.
R. Yehuda, A. Lehrner
semanticscholar   +1 more source

Past trauma and future choices: Differences in discounting in low-income, urban African Americans [PDF]

, 2018
BackgroundExposure to traumatic events is surprisingly common, yet little is known about its effect on decision making beyond the fact that those with post-traumatic stress disorder are more likely to have substance-abuse problems.
Berk-Clark, Carissa van den, Green, Leonard, Grucza, Richard A, Myerson, Joel   +3 more
core   +2 more sources

Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats

Journal of Orthopaedic Surgery and Research, 2021
Background The present study investigated the influence of ischemic postconditioning (I-postC) on the adjustment of renal injury after limb ischemia-reperfusion (I/R) injury, to elucidate the mechanisms of the Toll-like receptor 4 (TLR 4)/NF-κB signaling
Zhongdi Liu, Wei Huang, Yifan Chen, Zhe Du, Fengxue Zhu, Tianbing Wang, Baoguo Jiang   +6 more
doaj   +1 more source

A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation

Journal of Materials Science: Materials in Medicine, 2021
The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically performed on a plastic plate or a substrate of a single extracellular matrix constituent such as collagen or ...
Weidong Weng, Filippo Zanetti, David Bovard, Bianca Braun, Sabrina Ehnert, Tatiana Uynuk-Ool, Tina Histing, Julia Hoeng, Andreas K. Nussler, Romina H. Aspera-Werz   +9 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Are trauma research programs in academic and non-academic centers measured by equal standards? A survey of 137 level I trauma centers in the United States

Patient Safety in Surgery, 2021
Background American College of Surgeons level I trauma center verification requires an active research program. This study investigated differences in the research programs of academic and non-academic trauma centers.
Robert M. Madayag, Erica Sercy, Gina M. Berg, Kaysie L. Banton, Matthew Carrick, Mark Lieser, Allen Tanner, David Bar-Or   +7 more
doaj   +1 more source

Knowledge, attitudes, and behavior concerning dental trauma among parents of children attending primary school [PDF]

, 2016
BACKGROUND: Traumatic dental injuries occur frequently in children and adolescents. The purpose of the present study is to examine the levels of knowledge and behaviors regarding dental trauma among parents of children attending primary schools in the ...
Caggiano, G., DE GIGLIO, O, Montagna, Mt, Napoli, Christian, Quaranta, A, Trerotoli, P, Vaccaro, S   +6 more
core   +1 more source

A national evaluation of the effect of trauma-center care on mortality.

New England Journal of Medicine, 2006
BACKGROUND Hospitals have difficulty justifying the expense of maintaining trauma centers without strong evidence of their effectiveness. To address this gap, we examined differences in mortality between level 1 trauma centers and hospitals without a ...
E. Mackenzie, F. Rivara, G. Jurkovich, A. Nathens, K. Frey, B. Egleston, D. Salkever, D. Scharfstein   +7 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

A descriptive survey on the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for pelvic fractures at US level I trauma centers

Patient Safety in Surgery, 2019
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is not widely adopted for pelvic fracture management. Western Trauma Association recommends REBOA for hemodynamically unstable pelvic fractures, whereas Eastern Association for ...
Stephanie Jarvis, Michael Kelly, Charles Mains, Chad Corrigan, Nimesh Patel, Matthew Carrick, Mark Lieser, Kaysie Banton, David Bar-Or   +8 more
doaj   +1 more source