Results 81 to 90 of about 2,944,728 (379)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Complex Limb Injuries: Limb Salvage Versus Amputation—A Mini Review and Meta-Analysis

Advances in Orthopedics
Conclusion: Managing complex limb injuries effectively necessitates a comprehensive approach involving thorough assessment, multidisciplinary collaboration, and patient-centered care.
Athanasios Serlis, Panagiotis Sgardelis, Themistoklis Vampertzis, Konstantinos Rizavas, Panagiotis Poulios, Georgios Konstantopoulos   +5 more
doaj   +1 more source

A Comparison of PTSD, AUD, and MDD Symptom Patterns in Different Trauma Types [PDF]

, 2020
A Comparison of PTSD, AUD, and MDD Symptom Patterns in Different Trauma Types Elizabeth Crump, Depts. of Biology and Sociology, with Dr. Kaitlin Bountress, Virginia Institute of Psychiatric and Behavioral Genetics About 66% of college students have been ...
Crump, Elizabeth
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Violence indicators in Quebrada de Humahuaca, Jujuy, Argentina: The Regional Development Period from a regional perspective [PDF]

, 2014
Quebrada de Humahuaca (Jujuy, Argentina) has been extensively studied by archaeologists. Studies have been focused mainly on the Late Regional Development Period (1250 1430 AD), which has been defined as a time of social conflict.
Botta, Florencia Natalia, Seldes, Verónica   +1 more
core   +1 more source

From Individual To Social Trauma: Sources Of Everyday Trauma In Italy, The US And UK During The Covid-19 Pandemic

Journal of Trauma & Dissociation, 2020
The heterogeneity of COVID-19 experience and response for each individual is irrefutable; nevertheless, similarities can be observed between countries with respect to people’s psychological responses.
M. Masiero, M. Masiero, K. Mazzocco, K. Mazzocco, Catherine E. Harnois, M. Cropley, G. Pravettoni, G. Pravettoni   +7 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Trauma is danger [PDF]

Journal of Translational Medicine, 2011
Abstract Background Trauma is one of the leading causes of death in young adult patients. Many pre-clinical and clinical studies attempt to investigate the immunological pathways involved, however the true mediators remain to be elucidated.
Nancy Porterfield, Thomas A. Davis, Eric A. Elster, Eric A. Elster, Eric A. Elster, Paul F. Hwang, Paul F. Hwang, Paul F. Hwang, Dylan Pannell   +8 more
openaire   +5 more sources

Repeat Victimisation, Retraumatisation and Victim Vulnerability [PDF]

, 2015
: This study explores the contribution that traumatic experiences and psychological post-traumatic stress symptoms make to predicting subsequent revictimisation in a sample of violent crime victims.
Brooks, Matthew, Bryce, Joanne, Graham-Kevan, Nicola, Irving, May, Karwacka, Marta, Khan, Roxanne, Lowe, Michelle, Robinson, Phaedra, Stokes, Rachel, Willan, Victoria Jane   +9 more
core   +3 more sources

REM sleep in acutely traumatized individuals and interventions for the secondary prevention of post-traumatic stress disorder [PDF]

, 2020
Increasing evidence supports a close link between REM sleep and the consolidation of emotionally toned memories such as traumatic experiences. In order to investigate the role of sleep for the development of symptoms related to traumatic experiences ...
Bublitz, Jan Christoph, Danker-Hopfe, Heidi, Dresler, Martin, Kühn, Simone, Repantis, Dimitris, Tsamitros, Nikolaos, Wermuth, Katharina   +6 more
core   +1 more source