Results 41 to 50 of about 350,171 (303)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Variability in pelvic packing practices for hemodynamically unstable pelvic fractures at US level 1 trauma centers

Patient Safety in Surgery, 2019
Background Mortality from hemodynamically unstable pelvic fractures remains high. Guidelines offer varying care approaches including the use of pelvic packing (PP), which was recently adopted for potential control of bleeding for this condition. However,
Benoit Blondeau, Alessandro Orlando, Stephanie Jarvis, Kaysie Banton, Gina M. Berg, Nimesh Patel, Rick Meinig, Allen Tanner, Matthew Carrick, David Bar-Or   +9 more
doaj   +1 more source

Attitudes toward the adoption of eHealth amongst healthcare professionals in trauma surgery – the new digital normal?

BMC Health Services Research
Background As in many other countries, the Dutch emergency healthcare system is under pressure due to increasing numbers of patients, limited budgets, and constrained (human) resources (TraumaNet AMC 19 May, 2016; Int J Emerg Med 6:41, 2013).
Jelle Friso Spierings, Gijs Johan Antoon Willinge, Bas Anne Twigt, Sjoerd Repping, Marike Cornelia Kokke, Ruben van Veen, Detlef van der Velde   +6 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Institutional differences in management of compartment syndrome at academic and community-based trauma centers: A survey of Orthopaedic Trauma Association (OTA) members

OTA International, 2020
. Objectives:. The purpose of this study was to compare management of compartment syndrome at academic and community trauma centers and to identify any institutional variables that influence the number of adverse events reported to the hospital's peer ...
Matthew Klima, DO
doaj   +1 more source

Circulation first – the time has come to question the sequencing of care in the ABCs of trauma; an American Association for the Surgery of Trauma multicenter trial [PDF]

, 2018
Background The traditional sequence of trauma care: Airway, Breathing, Circulation (ABC) has been practiced for many years. It became the standard of care despite the lack of scientific evidence.
AAST Multi-Institutional Trials Committee, Anto, Vincent, Callcut, Rachael A, Duane, Therese M., Dubose, Joseph, Enniss, Toby, Ferrada, Paula, Garcia, Alberto, Inaba, Kenji, Khor, Desmond, McNutt, Michelle, Moore, Forrest O., Nygaard, Rachel M., Phelan, Herb, Schreiber, Martin A., Skarupa, David J., Smith, Kira, Sperry, Jason, Tabas, Irene, Turay, David   +19 more
core   +1 more source

Macroeconomic trends and practice models impacting acute care surgery [PDF]

, 2019
Acute care surgery (ACS) diagnoses are responsible for approximately a quarter of the costs of inpatient care in the US government, and individuals will be responsible for a larger share of the costs of this healthcare as the population ages.
Bernard, Andrew, Davis, Kimberly A., Doucet, Jay, Haider, Adil, Minei, Joseph P., Scherer, Tres, Staudenmayer, Kristan   +6 more
core   +3 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Management of severe trauma worldwide: implementation of trauma systems in emerging countries: China, Russia and South Africa

Critical Care, 2021
As emerging countries, China, Russia, and South Africa are establishing and/or improving their trauma systems. China has recently established a trauma system named “the Chinese Regional Trauma Care System” and covered over 200 million populations.
Jing Zhou, Tianbing Wang, Igor Belenkiy, Timothy Craig Hardcastle, Jean-Jacques Rouby, Baoguo Jiang, for the International Trauma Rescue & Treatment Association (ITRTA) Study Group   +6 more
doaj   +1 more source

Alcohol Interventions for Trauma Patients Treated in Emergency Departments and Hospitals: A Cost Benefit Analysis [PDF]

, 2007
Summarizes a study of whether screening for problem drinking and interventions to reduce alcohol intake in hospital trauma centers reduce the direct cost of injury-related health care.
Beth E. Ebel, David S. Salkever, Frederick P. Rivara, Larry M. Gentilello, Thomas M. Wickizer   +4 more
core