Results 61 to 70 of about 350,171 (303)

Trauma center funding: time for an update

Trauma Surgery & Acute Care Open, 2021
Background Uncompensated care (UC) is healthcare provided with no payment from the patient or an insurance provider. UC directly contributes to escalating healthcare costs in the USA and potentially impacts patient care. In Texas, there has been a steady
Manuel Lorenzo, Heather M Grossman Verner, Brian A Figueroa, Marcos Salgado Crespo, Joseph D Amos   +4 more
doaj   +1 more source

Traumatic brain injury related hospitalization and mortality in California. [PDF]

, 2013
ObjectiveThe aim of this study is to describe the traumatic brain injury (TBI) population and causes and identify factors associated with TBI hospitalizations and mortality in California.MethodsThis is a cross-sectional study of 61,188 patients with TBI ...
Bazargan-Hejazi, Shahrzad, Kermah, Dulcie, Lagbas, Clint, Pan, Deyu, Shaheen, Magda   +4 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Trauma center proliferation in the United States: concerns and potential solutions

OTA International
. There has been an increase in the number of Level I and II trauma centers across the United States in the past few decades. However, data suggest that access to trauma care remains poor in rural areas of the country, while in many urban areas, trauma ...
Niloofar Dehghan, MD, Lisa K. Cannada, MD, Ashraf N. El Naga, MD, Anna Miller, MD, Dan Schlatterer, DO, on behalf of the Orthopaedic Trauma Association Health Policy Committee   +5 more
doaj   +1 more source

American Association for the Surgery of Trauma Prevention Committee review: Family Justice Centers—a not-so-novel, but unknown gem

Trauma Surgery & Acute Care Open, 2021
The American College of Surgeons Committee on Trauma requires that trauma centers demonstrate adequate financial support for an injury prevention program as part of the verification process.
Deborah A Kuhls, Kazuhide Matsushima, Ronald Stewart, Tracey Dechert, Stephanie Bonne, Thomas K Duncan, Kimberly Joseph, Sharven Taghavi   +7 more
doaj   +1 more source

Success in the national care of pediatric trauma patients✰,✰✰

Journal of Pediatric Surgery Open
Background: Pediatric trauma patients should be treated at pediatric trauma centers, though not every patient can be transported to one. Our goal was to report outcomes for trauma patients at centers of varying levels of verification by the American ...
Kendall J Burdick, Aixa Perez Coulter, Michael Tirabassi   +2 more
doaj   +1 more source

Mortality Trends in Chest-Abdominal Trauma Patients Before and After the Establishment of Trauma Centers in South Korea [PDF]

Journal of Acute Care Surgery
Purpose We sought to assess mortality trends in chest-abdominal trauma patients, before and after the implementation of the Project Supporting Establishment of Trauma Centers (PSETC) in the Republic of Korea.
Dae Ryong Kang, Hye Sim Kim, Ji Young Jang, Ou-Hyen Kim, Kiyoung Kim, Un Young Choi, Jiwool Ko, Keum Seok Bae, Hongjin Shim   +8 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Impact of direct prehospital transport on mortality in patients with severe trauma based on the injury severity score: a nationwide observational study in the Republic of Korea [PDF]

Osong Public Health and Research Perspectives
Objectives Severe trauma remains a leading cause of death in the Republic of Korea. In response, regional trauma centers were established in 2012. This study evaluated the impact of direct prehospital transport to trauma centers on in-hospital mortality ...
Sun Ju Kim, KeunKyun Kim, Oh Hyun Kim, Chan Yong Park   +3 more
doaj   +1 more source