Results 31 to 40 of about 59,979 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Anterior Segment Trauma

open access: yes, 2016
Mechanical ocular trauma involving the anterior segment may result in damage to the conjunctiva, cornea, limbus, anterior chamber angle, iris, lens, and ciliary body. The mechanism of trauma (closed or open, blunt, penetrating, or perforating), force and
Lee, Richard K.   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Trauma ocular contuso: análise de 240 pacientes adultos atendidos em consultório particular de Florianópolis-SC. [PDF]

open access: yes, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Kriegl, Jean Philippe
core  

Traumatic Brain Injury in Admitted Patients with Ocular Trauma [PDF]

open access: yes
Objectives: To characterize the epidemiology of simultaneous traumatic brain injury (TBI) and ocular trauma. Materials and Methods: In this retrospective, observational study, de-identified data from patients admitted with ocular trauma and TBI was ...
Kevin Zhang   +4 more
core   +1 more source

COMMON OCULAR TRAUMA

open access: yesJournal of the American Medical Association, 1959
Physicians who are not ophthalmologists sometimes are obliged to treat eye injuries either because of the nature of their practice or because the situation demands immediate medical care. The minimum equipment includes some form of magnifier, a source of light, and a treatment tray, the contents of which are here listed. Chemicals splashed into the eye
openaire   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Trauma ocular na infância: estudo de 77 casos atendidos m consultório privado de Florianópolis (CS), entre 1996 e 2004. [PDF]

open access: yes, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Chevarria, Francisco de Calazans
core  

Propuesta de una ruta y vía Clínica para el mejoramiento de la calidad en el manejo y tratamiento del trauma ocular contuso basada en la evidencia [PDF]

open access: yes, 2023
Introducción: El trauma ocular es una causa frecuente de consulta en los servicios de oftalmología, mayormente en el género masculino. Dependiendo de la gravedad del daño ocasionado, el tratamiento representa un reto para el oftalmólogo, porque, se ...
Buitrago Torrado, Manuel Fernando
core   +1 more source

Animal and bird-related ocular trauma: a decade of experience from a tertiary referral eye hospital of Iran

open access: yesBMC Ophthalmology
Background This study aimed to explore ocular and periocular injuries resulting from animal and bird attacks among patients referred to a tertiary referral eye hospital of Iran over ten years (2014–2024).
Mohammadreza Mehrabi Bahar   +6 more
doaj   +1 more source

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