Results 51 to 60 of about 106,217 (300)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Microbial contamination of therapeutic contact lenses after photorefractive keratectomy: a prospective analysis

Journal of Ophthalmic Inflammation and Infection
Purpose The objective of this study was to examine bacterial contamination in therapeutic contact lenses (TCLs) utilized following photorefractive keratectomy (PRK) and to identify factors correlated to positive culture outcomes. Methods This prospective
Mohammad Soleimani, Omid Behjati Najafabadi, Mehrnaz Atighehchian, Alireza Razavi, Zohreh Abedinifar, Seyed Ali Tabatabaei, Hassan Asadigandomani   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science
Wet age‐related macular degeneration (wAMD), characterized by pathological choroidal neovascularization (CNV), is a leading cause of irreversible vision loss in the elderly.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
doaj   +1 more source

Questionnaire study to gain an insight into the manufacturing and fitting process of artificial eyes in children: an ocularist perspective [PDF]

, 2016
Purpose To gain an insight into the manufacturing and fitting of artificial eyes in children and potential improvements to the process. Method An online qualitative survey was distributed to 39 ocularists/prosthetists in Europe and Canada ...
A Clarke, A Fink, AA Ayanniyi, Bryce Dyer, D Raizada, E McColl, G Wu, GK Goel, H Jansen, HB McBain, Holly Chinnery, Karen Rees, N Starling, P Evans, P Garg, PD Converse, R Bibb, RK Gupta, S Li, S Sofaer, S Sofaer, Siamak Noroozi, Simon B. N. Thompson, SM Shortell, SR Shaikh, TJ Hoff, VC Braun, VW Willard, W Phillips, Y Bi   +29 more
core   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Trauma ocular [PDF]

, 2017
Esta webaula contempla as principais informações sobre o trauma ocular: Avaliação, tratamento e ...
Centro de Telessaúde HC/UFMG, Santos, Daniel Vítor Vasconcelos   +1 more
core  

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Causes and clinical manifestations of ocular trauma

Delta Journal of Ophthalmology, 2019
Purpose The aim of this work was to provide data about the causes and nature of ocular trauma and to find the relationship of these causes with age and sex. Patients and methods Patients with all types of eye injuries such as mechanical (by blunt object,
Elsayed M Elsayed, Sameh M Saleh, Dalia Sabry, Adel M Hassan   +3 more
doaj   +1 more source