Results 61 to 70 of about 28,755 (262)

Rapid Acute Physiology Score versus Rapid Emergency Medicine Score in Trauma Outcome Prediction; a Comparative Study

Emergency, 2016
Introduction: Rapid acute physiology score (RAPS) and rapid emergency medicine score (REMS) are two physiologic models for measuring injury severity in emergency settings.
Babak Nakhjavan-Shahraki, Masoud Baikpour, Mahmoud Yousefifard, Zahra Sadat Nikseresht, Samaneh Abiri, Jalaledin Mirzay Razaz, Gholamreza Faridaalaee, Mahboob Pouraghae, Sahar Shirzadegan, Mostafa Hosseini   +9 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

The role of the Revised Trauma Score in penetrating trauma [PDF]

Revista do Colégio Brasileiro de Cirurgiões
Introduction: The Revised Trauma Score (RTS) is one of the primary tools used to predict mortality in trauma patients. RTS is calculated at admission based on respiratory rate, systolic blood pressure, and Glasgow Coma Scale score. Its accuracy has been
STEFFANY BARBOSA REIS, MATHEUS PORTUGAL, MARIA TAVARES, MALU ADAN, GABRIEL SANTANA, ANA ROMEO   +5 more
doaj   +4 more sources

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Rapid Acute Physiology Score versus Rapid Emergency Medicine Score in Trauma Outcome Prediction; a Comparative Study

Archives of Academic Emergency Medicine, 2017
Introduction: Rapid acute physiology score (RAPS) and rapid emergency medicine score (REMS) are two physiologic models for measuring injury severity in emergency settings. The present study was designed to compare the two models in outcome prediction of
Babak Nakhjavan-Shahraki, Masoud Baikpour, Mahmoud Yousefifard, Zahra Sadat Nikseresht, Samaneh Abiri, Jalaledin Mirzay Razaz, Gholamreza Faridaalaee, Mahboob Pouraghae, Sahar Shirzadegan, Mostafa Hosseini   +9 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Leucocyte Profile of Adult Nigerians as Indicator of Severity Level of Acute Musculoskeletal Trauma

International Blood Research & Reviews, 2019
Leucocytosis, marked increase in the number of white blood cells (WBC) is a known physiological response to trauma. In recent times, several studies have asserted the absence of this response in Africans. In view of this, current study investigated the existence of, and prognostic implications of post-traumatic leucocytosis amongst adult Nigerians with
G. T. Olowe, S. E. Ehebha, E. N. Ekene, K. E. Asemota   +3 more
openaire   +2 more sources

Predicting mortality of geriatric trauma patients in Hong Kong—A comparison of scoring systems: GERtality score, Geriatric Trauma Outcome Score

Hong Kong Journal of Emergency Medicine
Introduction Various scoring systems have been devised in attempt to prognosticate and predict outcomes in trauma. This study aims to assess the comparative performance of the GERtality and Geriatric Trauma Outcome Score (GTOS) scores in predicting ...
Jeremy Ho Hei Chiu, Kai Yip Lai, Janice Hiu Hung Yeung, Chin San Leung   +3 more
doaj   +1 more source

Trauma do pâncreas: fatores preditivos de morbidade e mortalidade relacionados a índices de trauma Trauma of pancreas: predictor's factors of morbidity and mortality related to trauma index

Arquivos de Gastroenterologia, 2009
CONTEXTO: Embora incomuns, lesões traumáticas do pâncreas estão associadas a significativos níveis de complicações e mortalidade. OBJETIVO: Definir os fatores preditivos de morbidade e mortalidade em pacientes vítimas de trauma pancreático. MÉTODO: Foram
Henrique José Virgili Silveira, Mario Mantovani, Gustavo Pereira Fraga   +2 more
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source