Results 121 to 130 of about 214,727 (305)

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

SMART accelerates rate of cognitive gains in service members with mTBI and PTSD

Frontiers in Human Neuroscience
IntroductionThis randomized clinical trial (RCT) compared the efficacy of two cognitive rehabilitation (CR) protocols—Strategic Memory Advanced Reasoning Training (SMART) and Study of Cognitive Rehabilitation Effectiveness (SCORE)—in improving higher ...
Erin Venza, Jeffrey S. Spence, Jennifer Zientz, Cole Devlin, Jason Bailie, Jason Bailie, Jason Bailie, Andrew Darr, Andrew Darr, Andrew Darr, Ida Babakhanyan, Ida Babakhanyan, Ida Babakhanyan, Sandra Bond Chapman   +13 more
doaj   +1 more source

Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury

, 1992
S. Scott Panter, Alan I. Faden
openalex   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Trends in incidence of hospitalization for traumatic brain injury in Wisconsin from 1989 through 1992

, 1994
Robert L. Harmon, Mark Hodgson, James D. Cobb   +2 more
openalex   +1 more source

Corticosteroids in acute traumatic brain injury [PDF]

, 1998
David W. Newell, Nancy Temkin, Ross Bullock, Sung C. Choi   +3 more
openalex   +1 more source

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source

Outcome of traumatic brain injury at three years: A cohort study

, 1994
Gayle C. Fay, Kenneth M. Jaffee, Nayak L. Polissar, Shiquan Liao, J'May B. Rivara   +4 more
openalex   +1 more source

Medical Rehabilitation of Traumatic Brain Injury [PDF]

, 1997
Christopher D. Ward
openalex   +1 more source