Results 121 to 130 of about 583,291 (307)

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

Advanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang, Charles‐Francois Latchoumane, Avi Chopra, Md Marzan Sarkar, Chunki Kim, Nathan Gonsalves, Hsueh‐Fu Wu, John C. Sentmanat, Alan Liu, Isha Mhatre‐Winters, Aditya Mishra, Andrei G. Fedorov, Jay M. Patel, Nadja Zeltner, Steven L. Stice, Jason R. Richardson, Lohitash Karumbaiah   +16 more
wiley   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Validation of Strategic Memory Advanced Reasoning Training as an efficient and effective approach to treating warfighters with persistent cognitive complaints associated with mild traumatic brain injury

Frontiers in Neurology
IntroductionThis study directly compared the relative effectiveness of Strategic Memory Advanced Reasoning Training (SMART), which focuses on metacognitive strategies, to a traditional cognitive rehabilitation (CR) program previously developed and ...
Andrew J. Darr, Andrew J. Darr, Andrew J. Darr, Angela Basham, Angela Basham, Angela Basham, Jessica L. Ryan, Melissa Caswell, Melissa Caswell, Melissa Caswell, Juan Lopez, Juan Lopez, Juan Lopez, Jennifer Zientz, Erin Venza, Ida Babakhanyan, Ida Babakhanyan, Ida Babakhanyan, Sandra Chapman, Jason M. Bailie, Jason M. Bailie, Jason M. Bailie   +21 more
doaj   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

Advanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg, Le Zhen, Rebecca Darrow, Savannah Lawton, Lars Crawford, Robert Robinson, Steve Perlmutter, James D. Bryers, Buddy D. Ratner   +8 more
wiley   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

Advanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib, Tim‐Joshua Strauß, Jennifer Harre, Madeleine Goblet, Florian Klodwig‐Kirstein, Jana Schwieger, Michaela Kreienmeyer, Verena Scheper, Athanasia Warnecke, Nina Ehlert, Peter Behrens   +10 more
wiley   +1 more source

A dyad approach to understanding relationship satisfaction and health outcomes in military couples following service member and veteran traumatic brain injury

Frontiers in Psychiatry
ObjectiveUsing a dyadic approach, this study examined health and family outcomes in military couples following service member and veteran (SMV) traumatic brain injury (TBI), within the context of relationship satisfaction.MethodsParticipants included 164
Tracey A. Brickell, Tracey A. Brickell, Tracey A. Brickell, Tracey A. Brickell, Brian J. Ivins, Brian J. Ivins, Megan M. Wright, Megan M. Wright, Megan M. Wright, Jamie K. Sullivan, Jamie K. Sullivan, Jamie K. Sullivan, Louis M. French, Louis M. French, Louis M. French, Rael T. Lange, Rael T. Lange, Rael T. Lange, Rael T. Lange   +18 more
doaj   +1 more source

Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition

Neurosurgery, 2016
N. Carney, A. Totten, Cindy O'Reilly, J. Ullman, G. Hawryluk, M. Bell, S. Bratton, R. Chesnut, O. Harris, N. Kissoon, A. Rubiano, L. Shutter, R. Tasker, M. Vavilala, J. Wilberger, D. Wright, J. Ghajar   +16 more
semanticscholar   +1 more source

Recent Advances of Slip Sensors for Smart Robotics

Advanced Materials Technologies, EarlyView.
This review summarizes recent progress in robotic slip sensors across mechanical, electrical, thermal, optical, magnetic, and acoustic mechanisms, offering a comprehensive reference for the selection of slip sensors in robotic applications. In addition, current challenges and emerging trends are identified to advance the development of robust, adaptive,
Xingyu Zhang, Liao Wu, Shuai He, Zhao Sha, Yuwan Huang, Shuying Wu, Dewei Chu, Chun H. Wang, Shuhua Peng   +8 more
wiley   +1 more source

‘Their role has a lot of purpose beyond being just being about exercises’: a qualitative study of patients’ experiences of physiotherapy following a mild traumatic brain injury

BMJ Open Sport & Exercise Medicine
Following a mild traumatic brain injury (mTBI; also known as concussion), physiotherapists may be involved in injury identification, assessment and rehabilitation.
Alice Theadom, Sierra Keung, Duncan Reid, Jason Chua, Sam Jewell, Olivia Deadman   +5 more
doaj   +1 more source