Results 131 to 140 of about 262,861 (290)

Pre-Clinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases

, 2020
Michelle C. LaPlaca, J. Russell Huie, Hasan B. Alam, Adam D. Bachstetter, Hülya Bayır, Patrick S.F. Bellgowan, Diana M. Cummings, C. Edward Dixon, Adam R. Ferguson, Chantelle Ferland‐Beckham, Candace L. Floyd, Stuart H. Friess, Aristea S. Galanopoulou, Edward D. Hall, Neil G. Harris, Bridget E. Hawkins, Ramona Hicks, L.E. Hulbert, Victoria E. Johnson, Patricia Kabitzke, Audrey D. Lafrenaye, Vance Lemmon, Carrie W. Lifshitz, Jonathan Lifshitz, David J. Loane, Leonie Misquitta, Vahagn C. Nikolian, Linda J. Noble‐Haeusslein, Douglas H. Smith, Carol Taylor‐Burds, Nsini Umoh, Ольга Вовк, Aaron M. Williams, Margaret Young, Laila Zai   +34 more
openalex   +2 more sources

Functional motor improvement during inpatient rehabilitation among older adults with traumatic brain injury

, 2021
Emily Evans, Cicely Krebill, Roee Gutman, Linda Resnik, Mark R. Zonfrillo, Stephanie N. Lueckel, Wenhan Zhang, Raj G. Kumar, Kristen Dams-O’Connor, Kali S. Thomas   +9 more
openalex   +2 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Cell transplantation: history of development, bioetic and legal aspects, prospects for treatment traumatic brain injury

, 2021
Andrii I. Pavlov, Mykola V. Kadzhaya, Oleksandr S. Hotin   +2 more
openalex   +2 more sources

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Turning and suctioning traumatic brain injury patients lead to predictable and sustained episodes of intracranial hypertension [PDF]

, 2020
James Anstey
openalex   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Change of the zero-reference points for intracranial and arterial pressure results in altered neurocritical care management of severe traumatic brain injury patients [PDF]

Linus Réen, Henrik Wikström, Edward Visse, David Cederberg, Peter Siesjö, Niklas Marklund   +5 more
openalex   +1 more source

COGNITIVE DEFICITS FOUR DECADES AFTER MODERATE TO SEVERE, BUT NOT MILD TRAUMATIC BRAIN INJURY IN VIETNAM WAR VETERANS [PDF]

, 2021
Tia L. Cummins, Alby Elias, Fiona Lamb, Chris Rowe, Jennie Ponsford, Mal Hopwood, Victor L. Villemagne   +6 more
openalex  

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source