Results 191 to 200 of about 570,549 (333)

Cerebral Edema in Traumatic Brain Injury. [PDF]

open access: yesBiomedicines
Cardona-Collazos S   +6 more
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Basal cisternostomy for severe traumatic brain injury: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Sharafudeen A   +7 more
europepmc   +1 more source

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong   +10 more
wiley   +1 more source

Potential Predictors of Mortality in Adults with Severe Traumatic Brain Injury. [PDF]

open access: yesBrain Sci
Marta R   +5 more
europepmc   +1 more source

Pathophysiology of traumatic brain injury.

open access: yesBritish Journal of Anaesthesia, 2007
C. Werner, K. Engelhard
semanticscholar   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo   +17 more
wiley   +1 more source

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