Results 251 to 260 of about 824,886 (383)

Retraction: Topical application of daphnetin hydrogel for traumatic brain injury. [PDF]

Front Neurosci
Frontiers Editorial Office.
europepmc   +1 more source

RETRACTED: Fusco et al. Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury. Biology 2020, 9, 238 [PDF]

Roberta Fusco, Enrico Gugliandolo, Rosalba Siracusa, Maria Scuto, Marika Cordaro, Ramona D'Amico, Maurizio Evangelista, Angelo Peli, Alessio Filippo Peritore, Daniela Impellizzeri, Rosalia Crupi, Salvatore Cuzzocrea, Rosanna Di Paola   +12 more
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Safety of early chemoprophylaxis in traumatic brain injury patients. [PDF]

Surg Neurol Int
Hudson ML, Looman CF, Elder TA, Reisen B, Bourdow K, Morden P, Habib ZA, Adel JG.   +7 more
europepmc   +1 more source

Clinical Outcomes of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Patients with Traumatic Brain Injury or Spontaneous Intracerebral and Subarachnoid Hemorrhages: A Retrospective PILOT Study [PDF]

Minkeun Song, S. H. Jung, Kyeong-O Go, Kwangho Lee, Won Heo, Soo-Hyun Hwang, Hyun Park, Joung Hun Byun, Dong Hoon Kang, Jong Woo Kim, Sungdae Lim   +10 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

An update on diagnostic and prognostic biomarkers for traumatic brain injury

Expert Review of Molecular Diagnostics, 2018
Kevin K. W. Wang, Zhihui Yang, T. Zhu, Yuan Shi, R. Rubenstein, J. Tyndall, G. Manley   +6 more
semanticscholar   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Traumatic brain injury induces DNA damage in Drosophila. [PDF]

MicroPubl Biol
Katzenberger RJ, Ganetzky B, Wassarman DA.   +2 more
europepmc   +1 more source