Results 71 to 80 of about 712,838 (272)

Preconditioning for Traumatic Brain Injury [PDF]

Translational Stroke Research, 2012
Traumatic brain injury (TBI) treatment is now focused on the prevention of primary injury and reduction of secondary injury. However, no single effective treatment is available as yet for the mitigation of traumatic brain damage in humans. Both chemical and environmental stresses applied before injury have been shown to induce consequent protection ...
Anna Teresa Mazzeo, Anna Teresa Mazzeo, Shyam Gajavelli, Khadil Hosein, Shoji Yokobori, Shoji Yokobori, M. Ross Bullock, W. Dalton Dietrich   +7 more
openaire   +3 more sources

Unsupervised learning with GLRM feature selection reveals novel traumatic brain injury phenotypes [PDF]

arXiv, 2018
Baseline injury categorization is important to traumatic brain injury (TBI) research and treatment. Current categorization is dominated by symptom-based scores that insufficiently capture injury heterogeneity. In this work, we apply unsupervised clustering to identify novel TBI phenotypes. Our approach uses a generalized low-rank model (GLRM) model for
arxiv  

Traumatic brain injury: Age at injury influences dementia risk after TBI [PDF]

, 2015
Traumatic brain injury (TBI) is increasingly recognized as a risk factor for dementia. New data provide further support for this association and demonstrate the influence of age at injury and injury severity on dementia risk after TBI, revealing that ...
AC McKee, CW Hukkelhoven, DH Smith, GM Savva, M Susman, RC Gardner, S Fleminger, VE Johnson, VE Johnson, Victoria E. Johnson, William Stewart   +10 more
core   +1 more source

Inflammation and neuroprotection in traumatic brain injury.

JAMA Neurology, 2015
IMPORTANCE Traumatic brain injury (TBI) is a significant public health concern that affects individuals in all demographics. With increasing interest in the medical and public communities, understanding the inflammatory mechanisms that drive the ...
Kara N. Corps, Theodore L. Roth, D. McGavern   +2 more
semanticscholar   +1 more source

New Universal Theory of Injury Prediction and Prevention [PDF]

arXiv, 2009
The prediction and prevention of traumatic brain injury, spinal injury and general musculo-skeletal injury is a very important aspect of preventive medical science. Recently, in a series of papers, I have proposed a new coupled loading-rate hypothesis as a unique cause of all above injuries.
arxiv  

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury*

Critical Care Medicine, 2019
Objectives: Traumatic brain injury triggers multiple cell death pathways, possibly including ferroptosis—a recently described cell death pathway that results from accumulation of 15-lipoxygenase–mediated lipid oxidation products, specifically oxidized ...
Elizabeth M. Kenny, Emin Fidan, Qin Yang, T. Anthonymuthu, L. New, Elizabeth A. Meyer, Hong Wang, P. Kochanek, C. Dixon, V. Kagan, H. Bayır   +10 more
semanticscholar   +1 more source

Multi-directional dynamic model for traumatic brain injury detection [PDF]

arXiv, 2018
Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive finite element (FE) models of the brain to create tissue deformation metrics of brain injury. Here, we developed a 3
arxiv  

Forensic and clinical diagnosis in shaken baby syndrome , between child abuse and iatrogenic abuse [PDF]

, 2017
“Shaken baby syndrome” in child abuse cases is a challenge for pediatrician and forensic experts, often a diagnosis of exclusion, with overwhelming moral and legal implications.
Apostol, Irina, Belis, Vladimir, Calota, Relu G., Duncea, Roxana M.   +3 more
core   +3 more sources

The contribution of astrocytes and microglia to traumatic brain injury

British Journal of Pharmacology, 2016
Traumatic brain injury (TBI) represents a major cause of death and disability in developed countries. Brain injuries are highly heterogeneous and can also trigger other neurological complications, including epilepsy, depression and dementia.
Ila P Karve, Juliet M. Taylor, P. Crack
semanticscholar   +1 more source

Hypopituitarism following traumatic brain injury [PDF]

, 2015
Traumatic brain injury (TBI) is a worldwide public health problem and an important cause of hypopituitarism. The incidence of hypopituitarism following moderate to severe TBI varies in different studies and may occur as multiple or isolated hormonal
Attard, Carol, Vella, Sandro
core