Results 51 to 60 of about 583,291 (307)

Nurses’ contribution to relatives’ involvement in neurorehabilitation: Facilitators and barriers

Nursing Open, 2019
Aim The aim of the present study was to identify possible facilitators and barriers that differently positioned relatives are facing when being actively involved in the rehabilitation process of patients with traumatic brain injury.
Rikke Guldager, Karen Willis, Kristian Larsen, Ingrid Poulsen   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Unravelling the current shortfalls, challenges, and opportunities in traumatic brain injury

BMC Neurology, 2023
The brain is the control centre of the human body. Injury to the brain can have diverse and disabling effects. Yet there remain important unanswered questions for clinicians, those affected and their families.
A. Theadom, N. Andelic, V. Chavda, M. Pedersen   +3 more
doaj   +1 more source

Mechanisms of Blood–Brain Barrier Dysfunction in Traumatic Brain Injury

International Journal of Molecular Sciences, 2020
Traumatic brain injuries (TBIs) account for the majority of injury-related deaths in the United States with roughly two million TBIs occurring annually. Due to the spectrum of severity and heterogeneity in TBIs, investigation into the secondary injury is
Alison M. Cash, M. Theus
semanticscholar   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Resiliency and Mental Health Symptoms Among Active Duty Service Members With a History of Mild Traumatic Brain Injury

Archives of Rehabilitation Research and Clinical Translation
Objective: To evaluate the associations between resilience and emotional symptoms among service members (SMs) with mild traumatic brain injury (mTBI) and determine whether these relationships vary by the number of lifetime mTBI.
Rosemay A. Remigio-Baker, PhD, MPH, Lars D. Hungerford, PhD, Donald Marion, MD, Grace L. Reveles, RN, Angela G. Basham, MPH, Keith Stuessi, MD, Juan Lopez, BA, Jason M. Bailie, PhD   +7 more
doaj   +1 more source

Definition and epidemiology of mild traumatic brain injury.

Neuro-chirurgie, 2020
Background / objectives. The definition of mild traumatic brain injury (mTBI), also known as concussion, has been a matter of controversy, which makes comparison between studies. Incidence varies greatly from one country to another.
C. Lefèvre-Dognin, M. Cogné, V. Perdrieau, A. Granger, C. Heslot, P. Azouvi   +5 more
semanticscholar   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A Novel Method to Assist Clinical Management of Mild Traumatic Brain Injury by Classifying Patient Subgroups Using Wearable Sensors and Exertion Testing: A Pilot Study

Biomechanics, 2023
Although injury mechanisms of mild traumatic brain injury (mTBI) may be similar across patients, it is becoming increasingly clear that patients cannot be treated as one homogenous group.
Joshua P. McGeown, Mangor Pedersen, Patria A. Hume, Alice Theadom, Stephen Kara, Brian Russell   +5 more
doaj   +1 more source