Results 71 to 80 of about 583,291 (307)

Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines.

Pediatric Critical Care Medicine, 2019
Severe Traumatic Brain Injury in Infants, Children, and Adolescents in 2019: Some Overdue Progress, Many Remaining Questions, and Exciting Ongoing Work in the Field of Traumatic Brain Injury ResearchIn this Supplement to Pediatric Critical Care Medicine,
P. Kochanek, R. Tasker, N. Carney, Annette M. Totten, P. Adelson, N. Selden, C. Davis‐O'Reilly, Erica L. Hart, Michael J. Bell, S. Bratton, Gerald A. Grant, N. Kissoon, Karin E. Reuter-Rice, M. Vavilala, Mark S. Wainwright   +14 more
semanticscholar   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The Australian Traumatic Brain Injury Initiative: Statement of Working Principles and Rapid Review of Methods to Define Data Dictionaries for Neurological Conditions

Neurotrauma Reports
The Australian Traumatic Brain Injury Initiative (AUS-TBI) aims to develop a health informatics approach to collect data predictive of outcomes for persons with moderate-severe TBI across Australia. Central to this approach is a data dictionary; however,
Matthew K. Bagg, Amelia J. Hicks, Sarah C. Hellewell, Jennie L. Ponsford, Natasha A. Lannin, Terence J. O'Brien, Peter A. Cameron, D. Jamie Cooper, Nick Rushworth, Belinda J. Gabbe, Melinda Fitzgerald, Collaboration group, Collaboration group   +12 more
doaj   +1 more source

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

Nature Communications, 2019
Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause severe deficits in meningeal lymphatic drainage that begin within hours and ...
Ashley C. Bolte, A. Dutta, Mariah E. Hurt, I. Smirnov, M. Kovacs, Celia A. McKee, Hannah E Ennerfelt, Daniel A. Shapiro, Bao H. Nguyen, Elizabeth L. Frost, Catherine R. Lammert, J. Kipnis, J. Lukens   +12 more
semanticscholar   +1 more source

Detecting axonal injury in individual patients after traumatic brain injury

Brain : a journal of neurology, 2020
Jolly et al. develop a diffusion MRI pipeline for the diagnosis of axonal injury in individual patients with traumatic brain injury. They demonstrate the sensitivity of this pipeline for detecting axonal injury, show its relationship to clinical measures,
Amy E. Jolly, Maria Bălăeţ, A. Azor, D. Friedland, S. Sandrone, Neil S N Graham, K. Zimmerman, D. Sharp   +7 more
semanticscholar   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Recent advances in traumatic brain injury

Journal of Neurology, 2019
Traumatic brain injury (TBI) is the most common cause of death and disability in those aged under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income and middle-income countries making it a global health challenge.
Abdelhakim Khellaf, D. Khan, A. Helmy
semanticscholar   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Lifetime and childhood traumatic experiences as risk factors for persistent post-concussive symptoms among US service members

Frontiers in Neurology
ObjectivesThe objectives of this study were to investigate how the number of lifetime and childhood traumatic experiences relates to persistent post-concussive symptoms (PPCS) and mental health symptoms among US service members (SMs).MethodsThis study ...
Rosemay A. Remigio-Baker, Rosemay A. Remigio-Baker, Jan Kennedy, Jan Kennedy, Jan Kennedy, Lisa Lu, Lisa Lu, Lisa Lu, Matthew W. Reid, Matthew W. Reid, Matthew W. Reid, Jessica Bock, Jessica Bock, Michael Shaughness, Michael Shaughness, Alexis Nelson, Alexis Nelson, Mira R. Ananthanarayanan, Mira R. Ananthanarayanan, Mira R. Ananthanarayanan, Jamie Hershaw, Jamie Hershaw, Jamie Hershaw   +22 more
doaj   +1 more source

Severe Traumatic Brain Injury [PDF]

Neurosurgery, 2017
Background: Inadvertent hyperventilation is associated with poor outcomes from traumatic brain injury (TBI). Hypocapnic cerebral vasoconstriction is well described and causes an immediate and profound decrease in cerebral perfusion. The hemodynamic effects of positive-pressure ventilation (PPV) remain incompletely understood but may be equally ...
David L, Penn, John H, Chi, Mark R, Proctor   +2 more
openaire   +2 more sources