Results 41 to 50 of about 66,594 (309)

Influence of the shape, materials and occlusal mode of the maxillary first premolars on stress in noncarious cervical lesions

口腔疾病防治, 2019
Objective To study the stress distribution in noncarious cervical lesions (NCCLs) of maxillary first premolars under the conditions of different defect shapes, restorative materials and loading directions and to analyze the effect of different conditions
CAO Tingting, GE Chunhui, ZHANG Hongyan
doaj   +1 more source

Poly-arginine peptide R18D reduces neuroinflammation and functional deficits following traumatic brain injury in the Long-Evans rat [PDF]

, 2019
We have previously demonstrated that the poly-arginine peptide R18 can improve histological and functional outcomes following traumatic brain injury (TBI) in the Sprague–Dawley rat.
Anderton, Ryan S, Chiu, Li Shan, Clark, Vince W, Cross, Jane L, Knuckey, Neville W, Meloni, Bruno P   +5 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Intracranial pressure monitoring in normal dogs using subdural and intraparenchymal miniature strain-gauge transducers. [PDF]

, 2019
BackgroundMonitoring of intracranial pressure (ICP) is a critical component in the management of intracranial hypertension. Safety, efficacy, and optimal location of microsensor devices have not been defined in dogs.Hypothesis/objectiveAssessment of ICP ...
Dickinson, Peter J, LeCouteur, Richard A, Sturges, Beverly K, Tripp, Linda D, Udaltsova, Irina   +4 more
core  

Induced Ankylosis of a Primary Molar for Skeletal Anchorage in the Mandible as Alternative to Mini-Implants [PDF]

, 2015
Background Mesial protraction of mandibular posterior teeth requires increased anchorage to avoid undesired tooth movements. Orthodontic mini-implants have become a popular and successful way to increase skeletal anchorage in such cases.
Angelopoulou, Matina V., Halazonetis, Demetrios J., Koletsi, Despina, Vadiakas, George   +3 more
core   +2 more sources

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Severe Spasm of the Renal Artery after Blunt Abdominal Trauma Simulating End-Organ Infarction

Case Reports in Medicine, 2010
Traumatic occlusion of the renal artery is a serious injury. Management differs according to the grade of injury. In most circumstances, emergency surgical revascularization or endovascular intervention is required.
Adem Ucar, Aghakishi Yahyayev, Ayaz Agayev, Fatih Yanar, Selim Bakan, Mesut Bulakci, Tolga Akman, Ensar Yekeler   +7 more
doaj   +1 more source

Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. [PDF]

, 2017
Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic,
Aristizobal, Fabio A, Bledsoe, Andrea, Bohannon-Worsley, Laurie K, Borjesson, Dori L, Clark, Kaitlin C, Davidyan, Arik, Gray, Sarah N, Kol, Amir, LeJeune, Sarah S, Textor, Jamie A, Walker, Naomi J, Woolard, Kevin D   +11 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Trpv4 Activation Aggravates Temporomandibular Joint Osteoarthritis Via P38 Mapk Pathway

International Dental Journal
Aim or purpose: This study aimed to explore the underlying mechanisms after transient receptor potential vanilloid 4 (TRPV4) activation in disc during the progress of temporomandibular joint osteoarthritis (TMJOA).
Xiaotong Yu, Fu-Jia Yang, Yan Gu, Sheng-Jie Cui   +3 more
doaj   +1 more source