Results 31 to 40 of about 1,558,604 (252)

A great misfortune: second traumatic spinal cord injury

, 2002
Objective: A second and a separate traumatic spinal cord injury. which results in neurological deterioration, is very rare.
GENÇOSMANOGLU, B. E., GENCOSMANOGLU, BELGIN ERHAN, Kafadar, Ali Metin, M Hanci, Hanci, Mehmet Murat, A Kafadar, BE Gençosmanoğlu   +6 more
core   +1 more source

Mechanisms involved in chronic neuropathic pain after avulsion injury [PDF]

, 2010
PhDMotor vehicle accidents are the most common cause of injuries involving avulsion of spinal roots from the brachial or lumbosacral plexuses. This results in chronic intractable pain that is refractory to pharmacotherapy.
Chew, Daniel John
core   +2 more sources

Screening and outcomes of co-occurring traumatic brain injury among people with spinal cord injury: a scoping review

Journal of Rehabilitation Medicine
Objective: To map existing knowledge on screening and rehabilitation outcomes for co-occurring traumatic brain injury among people with traumatic spinal cord injury (SCI).
Deborah L. Snell, Phoebe Wynands, Jennifer Dunn, Joanne Nunnerley, Alice Theadom   +4 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Association Between Traumatic Spinal Cord Injury and Psychiatric Disorders, Mental Illness and Dementia: A Systematic Review and Meta-Analysis

Global Spine Journal
Study Design Systematic review and meta-analysis. Objectives Meta-analysis was used to evaluate the association between traumatic spinal cord injury and mental disorders, psychological disorders, and dementia onset, and to provide a scientific basis for ...
Li Li, Tiantian Wang, Huimin Du, Yuantong Zang   +3 more
doaj   +1 more source

Traumatic spinal cord injury in the north-east Tanzania – describing incidence, etiology and clinical outcomes retrospectively

Global Health Action, 2017
Background: Causes, magnitude and consequences of traumatic spinal cord injury depend largely on geography, infrastructure, socioeconomic and cultural activities of a given region.
Haleluya Moshi, Gunnevi Sundelin, Klas-Göran Sahlen, Ann Sörlin   +3 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Extracellular Vesicles Can Deliver Anti-inflammatory and Anti-scarring Activities of Mesenchymal Stromal Cells After Spinal Cord Injury

Frontiers in Neurology, 2019
Spinal cord injury is characterized by initial neural tissue disruption that triggers secondary damage and extensive non-resolving inflammation, which aggravates loss of function and hinders recovery.
Pasquale Romanelli, Pasquale Romanelli, Lara Bieler, Lara Bieler, Cornelia Scharler, Cornelia Scharler, Karin Pachler, Karin Pachler, Christina Kreutzer, Christina Kreutzer, Pia Zaunmair, Pia Zaunmair, Dominika Jakubecova, Dominika Jakubecova, Heike Mrowetz, Heike Mrowetz, Bruno Benedetti, Bruno Benedetti, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Ludwig Aigner, Ludwig Aigner, Ludwig Aigner, Eva Rohde, Eva Rohde, Eva Rohde, Mario Gimona, Mario Gimona, Dirk Strunk, Dirk Strunk, Sebastien Couillard-Despres, Sebastien Couillard-Despres, Sebastien Couillard-Despres   +34 more
doaj   +1 more source

Two-year mortality and end-of-life decisions after traumatic spinal cord injury: data from a Level 1 Trauma centre in the Netherlands

Journal of Rehabilitation Medicine, 2023
Objective: Literature shows high in-hospital mortality rates following end-of-life decisions in patients with traumatic spinal cord injury. This study investigated 2-year mortality and end-of-life decisions in patients with traumatic spinal cord injury.
Menco J.S. Niemeyer, Felix Peuker, Said Sadiqi, Monika C. Kerckhoffs, R. Marijn Houwert, Karlijn J.P. van Wessem, Marcel W.M. Post, Janneke M. Stolwijk   +7 more
doaj   +1 more source