Results 101 to 110 of about 662,983 (310)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conditions de travail : le taylorisme en question /

, 1974
Notes bibliogr.Numéro spécial de : "Sociologie du travail", ISSN 0038-1296, 16e année, n° 4, octobre-décembre ...
Bernoux, Philippe,pbd
core  

Qualité du travail, qualité au travail

, 2014
LHUILIER Dominique (coord.). Qualité du travail, qualité au travail. Toulouse : Octarès, 2014, 228 p. Cet ouvrage collectif est issu d'un séminaire organisé par le CRTD.
Rédaction
core   +1 more source

Du travail émotionnel au travail de santé

, 2023
Les transformations du traitement des émotions au travail se signalent par un glissement de la proscription des émotions à leur prescription, et ce, sur fond de ce nouveau modèle managérial de gestion des ...
Lhuilier, Dominique
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Deborah Lifchitz, une carrière d’ethnologue française dans l’entre-deux-guerres

Revue d’Histoire des Sciences Humaines, 2019
Marianne Lemaire
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Organisation, gestion productive et santé au travail, François Aballéa et Arnaud Mias (coord.) Octares 2014

, 2014
International audienceElaboré à partir d’un colloque organisé en 2010 du GRIS (Université de Rouen) et des RT 18 (« relations professionnelles») et 25 (« travail, organisation, emploi ») de l’AFS, il s’agit d’une somme de plus de 350 pages, rassemblant ...
Bouffartigue, Paul
core  

Forum travail

, 2015
Forum organisé par la Direction de la recherche et les laboratoires CRF, CRTD, DICEN, LISE et LIRSA du Cnam Le mercredi 8 avril 2015 à Paris Travail et engagement, Travail et management ou encore Travail et santé; voilà les thèmes que les chercheurs du ...
Rédaction
core   +1 more source