Results 151 to 160 of about 662,983 (310)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Inversion du genre. Corps au travail et travail des corps

open access: yes, 2012
« Inversion du genre. Corps au travail et travail des corps » Dossier coordonné par Yvonne Guichard-Claudic et Danièle Kergoat Cahiers du Genre, n° 42, 2007 - 264 p.
Doc du Cresppa
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Séminaire : Âge et travail

open access: yes, 2012
Séminaire annuel du CREAPT (Centre de Recherches et d’Études sur l’Âge et les Populations au Travail) Travail passé, activité et santé d’aujourd’hui : quels impacts des situations de travail ?
Rédaction
core  

Kategorien des Geschlechts in der Arbeitswelt

open access: yesTrivium, 2015
Michel Lallement   +3 more
doaj   +1 more source

Lésions sentinelles et indicateurs de sévices chez l’enfant. [PDF]

open access: yesCMAJ
McDowell H   +4 more
europepmc   +1 more source

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