Results 41 to 50 of about 1,075,156 (295)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Fourierist legacies: from the ‘Right to the Minimum’ to ‘Basic Income’ [PDF]
, 2001 The origins of the idea of a “basic income” remain to be fully explored. An idea with currency mainly in Europe, a basic income is conventionally defined as an income unconditionally granted to all on an individual basis, irrespective of the level of any
Cunliffe, John, Erreygers, Guido
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Os sindicatos brasileiros em face das inovações tecnológicas e organizacionais
Dados: Revista de Ciências Sociais, 2008 Dans cet article, on étudie l'action syndicale qui cherche à influencer les processus d'innovation technologique et organisationnelle dans les entreprises.
Fernando Coutinho Cotanda
doaj +1 more source
Travail informel, travail illégal
Calenda, 2023 Ce numéro de L’Homme et la société entend s’intéresser à la diversité des formes et des acteurs du travail informel et illégal. Trop souvent associé aux économies dites « en développement », et présenté comme un phénomène de marge, nécessairement transitoire ou minoritaire, le travail informel ou illégal a pourtant joué et continue de jouer un rôle ...
openaire +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Stratégie économique, politique et industrielles du syndicalisme [PDF]
, 1978 Ce document politique adopté par le Conseil exécutif du Congrès du travail du Canada a été ratifié lors de la douzième Assemblée statutaire de ce groupement tenue à Québec en avril ...
, Congrès du travail du Canada
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source