Results 111 to 120 of about 3,774,487 (407)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
COVID-19 severity and corticosteroid treatment have minimal effect on specific antibody production
Background Dexamethasone is currently administered for Coronavirus disease 2019(COVID-19); however, there are concerns about its effect on specific antibodies’ production. The aim of this study was to evaluate whether specific antibodies were affected by
Takato Nakamoto+16 more
doaj +1 more source
ObjectiveTo detect enterohemorrhagic Escherichia coli (EHEC) O157:H7, visualization recombinant enzyme polymerase amplification (RPA) detection and real-time fluorescence RPA detection methods were established based on RPA technology.MethodsPrimers and ...
XU Ying+3 more
doaj +1 more source
How Effective are Toll Roads in Improving Operational Performance? [PDF]
The main focus of this research is to develop a systematic analytical framework and evaluate the effect of a toll road on region’s traffic using travel time and travel time reliability measures. The travel time data for the Triangle Expressway in Raleigh,
Mathew, Sonu, Pulugurtha, Srinivas S.
core +1 more source
Impact of Locally Suppressed Wave sources on helioseismic travel times
Wave travel-time shifts in the vicinity of sunspots are typically interpreted as arising predominantly from magnetic fields, flows, and local changes in sound speed.
A. C. Birch+43 more
core +1 more source
The influence of land use and mobility policy on travel behavior : a comparative case study of Flanders and the Netherlands [PDF]
Numerous transportation studies have indicated that the local built environment can have an important effect on travel behavior; people living in suburban neighborhoods travel more by car than people living in urban neighborhoods. In this paper, however,
De Vos, Jonas
core +4 more sources
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
HIV Vaccine Research: The Challenge and the Way Forward
Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority.
Hai-Bo Wang, Qiu-Hua Mo, Ze Yang
doaj +1 more source
624 Establishing the Influence of Technology on Travel Behaviour through Bibliometric Analysis [PDF]
The role of technology in altering consumer behaviour is not hidden. Behavioural investigations concentrate on how people choose, pay for, consume, and reject items and services, theories, and events to meet their requirements.
Shilpi GUPTA+2 more
doaj +1 more source
Learning poly-synaptic paths with traveling waves [PDF]
Traveling waves are commonly observed across the brain. While previous studies have suggested the role of traveling waves in learning, the mechanism is still unclear. We adopted a computational approach to investigate the effect of traveling waves on synaptic plasticity. Our results indicate that traveling waves facilitate the learning of poly-synaptic
arxiv