Results 141 to 150 of about 3,411,914 (309)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The Empath’s Travel Log

open access: yes, 2015
Cynthia Marie Hoffman Studner said of the poem, This is an ambitious poem that delivers on empathy, just as promised. The poem establishes a metaphor of a “taught thread” that pulls together the traveler and an “orange-coated mutt” spotted in Italy, and
Thompson, PamEla J.
core  

Economic evaluations of antibiotic stewardship programmes 2015–2024: a systematic review

open access: yesSwiss Medical Weekly
BACKGROUND: Numerous studies have demonstrated the effectiveness of Antibiotic Stewardship Programmes in reducing antibiotic resistance and healthcare costs.
Jasmin Huser   +4 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The role of travel time budgets – Representation of a demand derived from activity participation [PDF]

open access: yes
The paper exams the relationships between travel and activity times, in 7 travel surveys from 4 French and 3 Swiss cities, observed at two different periods.
Iragaël Joly
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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