Results 71 to 80 of about 1,125,796 (256)

Indonesia 2006

open access: yes, 2006
Tourist map with roads emphasized. Relief shown by gradient tints and spot heights. Depths shown by gradient tints. Includes notes, indexes of places, publisher's index map, publisher's map list, and color illustrations.Color;1:2,400 ...
International Travel Maps (Firm);
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Texas Travel Log

open access: yes, 1983
Newsletter dedicated to traveling in Texas, including information about news, locations, and events of interest to visitors as well as statistics and summaries of travel in the ...
Texas. Travel and Information Division.
core   +1 more source

Everyday Discourses of Climate Delay in Opposition to Low Traffic Neighbourhoods

open access: yesActive Travel Studies
Climate change is unequivocal, yet public conversations negating the need for urgent action remain. Discourses of climate delay, which create the sense of intractable obstacles to action, are one form of this.
David Fevyer   +4 more
doaj   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Travel choices in Scotland - the effect of local accessibility on non-work travel [PDF]

open access: yes, 2005
Accessibility features prominently in the developing transport policies of both the United Kingdom Government and the devolved Scottish Executive which aim to promote social inclusion in particular and the integration of transport and land use planning ...
Ferguson, N.S.   +2 more
core  

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