Results 81 to 90 of about 1,125,796 (256)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Women on the Move: How Socio-Economic Background Through Lifestyle Shapes Travel Behavior to Bali

open access: yesJurnal Aplikasi Manajemen
Tourism is a crucial sector for economic growth, and understanding the factors that influence travel behavior is essential for developing effective strategies.
Ni Made Dyah Ryana Kurniasari   +1 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Visualization and real-time fluorescence RPA detection methods for enterohemorrhagic Escherichia coli O157:H7

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo detect enterohemorrhagic Escherichia coli (EHEC) O157:H7, visualization recombinant enzyme polymerase amplification (RPA) detection and real-time fluorescence RPA detection methods were established based on RPA technology.MethodsPrimers and ...
XU Ying   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Intermediality, Multimodality and Medial Chronotopes: A Comparison between the Travel Book and the Travel Blog

open access: yesCaracteres: Estudios Culturales y Críticos de la Esfera Digital, 2014
Using Bakhtin’s “chronotope”, this paper advances a comparison between the travel book Il mondo oltre il fiume dei peschi in fiore by Sino-Italian Bamboo Hirst and the travel blog Emil’s Trip to China, by American Emil Kang.
Stefano Calzati
doaj  

COVID-19 severity and corticosteroid treatment have minimal effect on specific antibody production

open access: yesBMC Infectious Diseases
Background Dexamethasone is currently administered for Coronavirus disease 2019(COVID-19); however, there are concerns about its effect on specific antibodies’ production. The aim of this study was to evaluate whether specific antibodies were affected by
Takato Nakamoto   +16 more
doaj   +1 more source

Man vs Woman: Exploring Organizational Support, Job Satisfaction, and Trust in Travel Industry Employee Commitment

open access: yesJurnal Aplikasi Manajemen
Attention to employee welfare is a significant focus in human resource management. Companies that pay attention to employee welfare often see increased employee commitment.
Theresia Salsa Purnama Renggi   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Shared Memories, Shared Stories: How Memorable Travel Experiences, Destination Attachment, and Tourist Satisfaction Drive sWOM Intentions

open access: yesJurnal Aplikasi Manajemen
Social media has become an important platform for sharing travel experiences, where information tourists share can influence prospective tourists' perceptions and decision-making processes. Understanding what motivates tourists, particularly Generation Z
Natasya Octaviani   +1 more
doaj   +1 more source

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