Results 101 to 110 of about 965,882 (301)

The peculiarities of contractual relationship between travel operators, travel agents and tourists [PDF]

open access: yes, 2014
Розглянуто особливості договірних взаємовідносин, які виникають між ключовими суб’єктами туристичної діяльності: туроператором, турагентом і туристом. З’ясовано, що основними документами, які регулюють їх діяльність, є агентський договір та договір на ...
Danylenko-Kulchytska, Victoriya
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Tecnologia de informação nas Agencias de Turismo: uma analise de como as agencias estão utilizando esse recurso para se manter competitiva

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2007
The development of technology of information for trade of tourism especially the travel agency and hotel undertaking are going one instrument fundamental for competitive require actually.
Gomes de Moraes, Adriana
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

SOCIAL VISIBILITY OF CONSUMPTION AS A PHENOMENON DRIVING THE SELF-EXPRESSION AND TRAVEL INTENTION OF MUSLIM TOURISTS [PDF]

open access: yesGeo Journal of Tourism and Geosites
This study aims to empirically predict the relationship between social visibility of consumption and word-of-mouth communication (e-WOM) and travel intention, with self-expression as the mediator variable.
Yusuf BİLGİN
doaj   +1 more source

Travel Agencies and Gastronomy Tourism: Case of Iata Member A-Class Travel Agencies

open access: yesJournal of Gastronomy Hospitality and Travel (JOGHAT), 2018
This research was made in order to show to what extend IATA Member A-Class Travel Agencies, which operate in Istanbul, how benefit from the gastronomy tourism. Parallel to this aim data was collected via content analysis method from the 244 websites of the IATA member travel agencies, which are registered to TURSAB and operate in Istanbul, between ...
CANKÜL, Duran, DEMİR, İbrahim
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Pembuatan Website Pada Perusahaan "Sky High Tour & Travel Agency" [PDF]

open access: yes, 2016
Sky High Tour & Travel Agency is a tour company and travel agency in the area of South Surabaya, which offers services in the field of Tourism.
Cahyadi, M. (Machael)   +2 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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