The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Role of Tourism and Travel Agencies in Encouraging Domestic Tourism Case Study of Al Najah Tourism & Travel Agency in the Province of Chlef [PDF]
مجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019 This research paper aims to identify the role of tourism and travel agencies in promoting domestic tourism by dropping the study on the case of tourism and travel agency "al najah" of chlef. The study has dealt with the subject through two sides.
FERRAH Oussama, ABDELAZIZ Rahma
doaj
The organizing process in travel agencies: aesthetic, ethnomethodological and practices influences
Revista Brasileira de Pesquisa em Turismo, 2014 In the context of tourism organizations, the relationship between the process of organizing and learning and generating knowledge is something latent, in particular those of small and medium size as are the vast majority of travel agencies in Brazil ...
Marcelo de Souza Bispo
doaj +1 more source
Concept of Improvement Services in Travel Agency. [PDF]
, 2007 Bakalářská práce se zabývá analýzou služeb cestovní kanceláře Cílka, s.r.o. První část je zaměřena na výklad pojmů, problematiku cestovního ruchu, marketing služeb a metody analýzy konkurence, jejich produktů a služeb.
Procházková, Ivana
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Internet as an Important Tool in the Tourism Industry and its Use in Customer Service
Expert Journal of Marketing, 2018 The tourism sector is one of the most important business sectors in Greece. The term “online travel agency” refers to the transfer to the Internet of all or part of the tourism services offered by a real travel agency.
Nikolaos TZIORAS
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The First Complaint: An Approach to the Admission of Child-Hearsay Statements Under the Alaska Rules of Evidence [PDF]
, 2010 The Swedish Transport Agency has for a long time collected data on a monthly basis for different variables that are used to make predictions, short projections as well as longer projections.
Arvid, Odencrants, Dennis, Dahl
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The customer market practices of the travel agency industry in the Gauteng Province of South Africa [PDF]
, 2011 Relationship marketing stresses the importance of continuous interaction between the seller and the buyer in order to cultivate a long-term, mutually beneficial relationship.
Roberts-Lombard, M.
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