Results 71 to 80 of about 965,882 (301)

Travel agents as market mavens: An empirical study on travel agencies in Izmir [PDF]

open access: yes, 2017
Despite the developments in computer-mediated communication after the advent of the Internet, traditional word-of-mouth (WOM) marketing is still influential on consumers’ buying decision processes. As one of the WOM influencer groups, market mavens are
Doğru, Hümeyra   +2 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Travel Agency Information System Design [PDF]

open access: yes, 2010
Import 29/09/2010V předložené diplomové práci je zpracován projekt informačního systému cestovní kanceláře. V práci nejprve popisuji problematiku tvorby informačních systémů.
Sládeček, Jakub
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Undoing one’s past

open access: yesFilosofia Unisinos, 2018
In contemporary research on memory, the idea of mental time travel (MTT) has been connected, at the functional level, with planning and imagining what might occur in one’s future.
Eduardo Vicentini de Medeiros
doaj   +1 more source

KARAKTERISTIK, MOTIVASI DAN PERSEPSI WISATAWAN MANCANEGARA KE DESA WISATA TRUNYAN, KINTAMANI

open access: yesJurnal IPTA, 2020
Tourists who travel to a tourism village certainly have different characteristics, motivations, and perceptions. These three things are very important to be identified, because they can become a reference material for the local community and the ...
I Putu Angga Pratama   +2 more
doaj   +1 more source

Quality Analysis of Provided Services of the Selected Travel Agency [PDF]

open access: yes, 2019
Tato bakalářská práce se zaměřuje na analýzu kvality poskytovaných služeb cestovní kanceláře Valaška. Cílem práce bylo zjistit stávající spokojenost zákazníků s kvalitou služeb pobočky cestovní kanceláře Valaška ve Valašském Meziříčí a na základě ...
Lukášová, Michaela
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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