Results 91 to 100 of about 2,501,529 (292)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2017 Australian governments invested significant sums in voluntary travel behaviour interventions in the 1990s and 2000s. The Travel Blending and Individualised Marketing (IndiMark) schemes based on social marking were highly controversial.
Yen, Barbara +6 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Dark Tourism Motivations, Experience, Emotions and Behaviour of Tourists [PDF]
African Journal of Hospitality, Tourism and LeisureThe purpose of this study is to explore travel motivations at dark tourism sites and the impact of dark tourism motivations on tourist experience. The study also tried to examine the impact of experience on tourist emotions and behaviour at dark tourism ...
Hafizullah DAR, Amolakdeep KAUR
doaj +1 more source
Exploring the relationship between land-use system and travel behaviour - some first findings [PDF]
Theories on the reciprocal relationship between land-use and transport address changes in locational decisions and travel behavior of private actors (households and firms) due to alternations in the transport system, respectively land-use system ...
Veronique Van Acker, Frank Witlox
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
ANALYSIS OF RAILWAY USER TRAVEL BEHAVIOUR PATTERNS OF DIFFERENT AGE GROUPS
IATSS Research, 2009 In recent years, there have been requirments for a transport environment that will foster the development of safe, comfortable townships. The study of urban activities amid an aging society and effective use of public transport modes in addressing ...
Takamasa AKIYAMA
doaj +1 more source
, 2021 Torism RESET and the Black Travel Alliance have partnered to release a new website. The website, called the “History Of Black Travel” is purposed to educate the industry and the people we serve about the perspectives and histories of African peoples ...
Black Travel Alliance
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source