Results 71 to 80 of about 2,501,529 (292)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Travel behaviour under fuel constraint study: TACA SIM [PDF]
, 2009 Future oil availability and cost has been discussed recently in international agency and government reports. Transportation is the fastest-growing and largest user of oil. Future personal transportation will continue to be fuelled by oil. However, as the
Andre Dantas +8 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
IATSS Research, 2000 Some lessons have been learnt about travel behaviour, e.g. how travel time consumption seems constant and independent of the economic and social situation and how improvements in speed increase trip length.
S. Olof GUNNARSSON
doaj +1 more source
Journal of Advanced Transportation, 2020 Based on the price-quantity adjustment behaviour principle of the non-Walrasian equilibrium theory, this paper adopted a new QUE (quantity adjustment user equilibrium) criterion to formulate the route comfort choice behaviour.
Zhongxiang Huang +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Why (don’t) we travel sustainably? Generation Z and the theory of planned behaviour
TourismGeneration Z, the cohort born approximately between 1995 and 2010, represents a generation shaped by digital technology, social connectivity and global awareness, who exhibit distinct attitudes, behaviours and values that differentiate them from ...
Marija Vukadin Milojević +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Travel Behaviour of Online Shoppers in Sweden
Transport and Telecommunication, 2015 Online shopping opportunities are transforming travel behaviour for shopping and could potentially reduce the overall travel demand. Despite numerous studies on online shopping, only a few have taken an approach that includes trips for all travel ...
Hiselius Lena Winslott +2 more
doaj +1 more source