Results 51 to 60 of about 247,343 (260)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Culture & History Digital Journal, 2012 As part of a reflection on Atlantic history, I intend to reread the travel literature written by Europeans who stayed briefly at the Brazilian shore, so as to learn about the Portuguese empire -and particularly Brazil- from the inside and understand how ...
Ângela Domingues
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Indialogs: Spanish Journal of India Studies, 2016 In 1908 the Catalan stage designer Oleguer Junyent and his friend Mariano Recolons set off on a trip around the world. They spent eleven months visiting Egypt, India, Australia, China, Japan, Canada and the United States.
Carolina Plou Anadón
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lea, 2015 This article presents an unpublished diary (March-April 1932) of Vittoria Contini Bonacossi, held by the Archivio di Stato in Florence. Analysis of this document shows how the diary goes beyond the typical characteristics of this literary genre – as a ...
Diego Salvadori
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
AnglesBorn in Sheffield in the 1980s, in a dual-heritage working-class family, Johny Pitts came to fame in 2019 with the publication of Afropean: Notes on Black Europe.
Fanny Robles
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source