Results 61 to 70 of about 247,343 (260)
AfriquesSwedish merchant C.H. Braad’s illustrated description in 1750 of the rulers, people, crops, livestock and wildlife of ‘Johanna’ (Anjouan/Nzwani) in the Comoros is translated, with extensive annotations, from part of his manuscript account of a voyage to ...
Jeremy Franks†, Anthony S. Cheke
doaj +1 more source
Iceland in the Eighteenth Century: An Island Outpost of Europe?
Sjuttonhundratal, 2013 The aim is to define Iceland’s relationship with Europe during the eighteenth century. Though Iceland, an island in the mid-Atlantic, was geographically isolated from the European continent, it was in most respects an integral part of Europe. Iceland was
Anna Agnarsdóttir
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Eating on the Eve of the Early Modern Period
ClothoBetween 1485 and 1487, the Patriarch of Aquileia sent the bishop of Caorle (Italy) to the Alps-Adriatic region to re-consecrate churches, chapels, and cemeteries that had been desecrated during the Turkish invasions. Among the travelers was the bishop’s
Stephan F. Ebert
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Marco Robecchi, Jean le Long et la traduction du Liber peregrinationis de Riccold de Monte di Croce
Perspectives Médiévales, 2020 Marco Robecchi
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Literature, or the travelling tattoo
Francosphères, 2017 This essay considers Kanak author Déwé Gorodé’s 2009 novel Graines de pin colonnaire and Tahitian author Stéphanie Ari’irau Richard’Vivi’s 2006 novel Matamimi, ou La vie nous attend as ‘mobile manuscripts’: dialogic, literary border-crossings that facilitate communication and connections in Oceania.
openaire +3 more sources