Results 101 to 110 of about 317,764 (294)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Travelling with medicines [PDF]

open access: yesAustralian Prescriber, 2006
Summary The overseas traveller needs to plan ahead to ensure medicines are available and used properly. This planning needs to take account of relevant legal, customs and Pharmaceutical Benefits Scheme restrictions. Medicines should be transported in their original packaging whenever possible and refrigeration during flight is seldom necessary.
openaire   +1 more source

The provision of sexual and reproductive health information and services to travellers: an exploratory survey of Australian travel medicine clinicians [PDF]

open access: yes
Background International travel can increase the risk of exposure to infectious diseases including sexually transmissible infections (STI). Pre-travel medical consultation provides an opportunity for travel-related health risk assessments and advice ...
Fowler, James A.   +11 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A rare case of candida osteomyelitis of the mandible associated with osteoradionecrosis and biofilm formation

open access: yesIDCases
Candida osteomyelitis, in general, is a relatively rare manifestation compared to its bacterial counterparts. The mandible's involvement is rarer, lacking established management and fewer guidelines. Herein, we aim to illustrate the significant challenge
Gabriel A. Godart   +2 more
doaj   +1 more source

‘What are you going to do, confiscate their passports?’ Professional perspectives on cross-border reproductive travel [PDF]

open access: yes, 2013
Objective: This article reports findings from a UK-based study which explored the phenomenon of overseas travel for fertility treatment. The first phase of this project aimed to explore how infertility clinicians and others professionally involved in ...
Pacey, Allan   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Travel health advisory group: activities of a join travel industry and travel medicine group promoting healthy travel [PDF]

open access: yes, 2008
Objective: The Australian Travel Health Advisory Group (THAG), established in 1997, is a joint initiative between the travel industry and travel medicine professionals that aims to promote healthy travel amongst travellers.
Zwar, N., Leggat, P.A.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

First documented case of visceral leishmaniasis with rare colonic involvement in an immunocompetent adult in Slovakia

open access: yesBMC Infectious Diseases
Background This article presents the first documented case of visceral leishmaniasis in an adult patient in Slovakia, with an unusual involvement of the colon.
Ondrej Zahornacky   +6 more
doaj   +1 more source

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