Results 91 to 100 of about 990,169 (288)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Food safety regulations and surveillance in Bangkok, Thailand - with 5-year real world data

open access: yesTropical Diseases, Travel Medicine and Vaccines
Background Food tourism is one of the major attractions in Thailand. Food safety plays an important role in ensuring the confidence and health of both travelers and locals.
Narissara Techavachara   +3 more
doaj   +1 more source

What do Portuguese Travellers Know About Malaria? Pre-Travel Medicine Appointment Evaluation

open access: yesActa Médica Portuguesa, 2018
Introduction: The knowledge of transmission, prevention and symptoms of malaria is essential for travellers’ safety. In real life, what do Portuguese travellers know about malaria before a Travel Medicine consultation?
Joana Cepeda   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An open-ended future: In defense of a new humanism [PDF]

open access: yes
The edge between technology and humanism is discussed. Advances in biology, in medicine, energy technology, tools and weapons, communications, psychology, problem solving and information storage, transportation, and other fields are presented. Ecology in
Vonputtkamer, J.
core   +1 more source

Barriers to and facilitators of antiretroviral therapy adherence in Nepal: a qualitative study. [PDF]

open access: yes, 2012
Patient's adherence is crucial to get the best out of antiretroviral therapy (ART). This study explores in-depth the barriers to and facilitators of ART adherence among Nepalese patients and service providers prescribing ART. Face-to-face semi-structured
Freeman, J.V.   +4 more
core   +3 more sources

Medical Tourism Attraction of Tehran Hospitals [PDF]

open access: yesInternational Journal of Travel Medicine and Global Health, 2013
Introduction: Today the market of medical tourism is growing as one of the competitive and profitable industries in the world. The aim of this study was to determine medical tourist attraction in Tehran hospitals.
Ali Ayoubian   +2 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

J Travel Med [PDF]

open access: yes
IntroductionAs international travel increases, travellers may be at increased risk of acquiring infectious diseases not endemic in their home countries. Many journal articles and reference books related to travel medicine cite that between 22\u201364% of

core  

Home - About - Disclaimer - Privacy