Results 171 to 180 of about 159,475 (252)

Geographical barriers to surgical treatment for cataract among California Medicare beneficiaries. [PDF]

J Cataract Refract Surg
Murillo K, Kitayama K, Yu F, Tseng VL, Coleman AL.   +4 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Understanding the synergies among factors shaping parents' intention to use walking school buses. [PDF]

NPJ Sustain Mobil Transp
Zannat KE, Lizana M, Wang JYT, Watling DP.   +3 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Reimagining Data for Equity: Reaching the Unreached Map Explorer for Localized Public Health Intelligence in the Western Pacific Region. [PDF]

JMIR Public Health Surveill
Hashmi S, Budts AL, Meurrens V, Stow JS, Morishita F, Yadav RP.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Modelling multidimensional access to inpatient paediatric emergency hospital care in Kenya: A geospatial-statistical approach

Musau MM, Muchiri SK, Odipo E, Onyango SA, Museka C, Beňová L, Linard C, Okiro EA, Snow RW, Macharia PM.   +9 more
europepmc   +1 more source

Differences in Baseline Demographic Characteristic and Complexity of Patients Based on Distance Traveled to Academic Center for Surgery. [PDF]

Arthroplast Today
Vennitti C, Burke J, Gandhi S, Fontana J, Novicoff W, Borsinger T.   +5 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source