Results 111 to 120 of about 63,289 (291)

Prediction Intervals for Bus Travel Time Based on Road Segment Sharing, Multiple Routes’ Driving Style Similarity, and Bootstrap Method

open access: yesApplied Sciences
Providing accurate information about bus travel times can help passengers plan their itinerary and reduce waiting time. However, due to various uncertainty factors and the sparsity of single-route data, traditional travel time predictions cannot ...
Zhenzhong Yin   +3 more
doaj   +1 more source

Measuring the structural determinants of urban travel demand [PDF]

open access: yes
To be best prepared for tomorrow's cities we need to forecast urban travel demand. To this end, this study calibrates an urban travel demand model, which uses the principal structural variables that have been identified in the literature.
Stéphanie Souche
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

SPECIFICATION OF A MODEL TO MEASURE - THE VALUE OF TRAVEL TIME SAVINGS FROM BINOMIAL DATA [PDF]

open access: yes
This paper develops a semiparametric methodology for the evaluation of the distribution of the value of travel time savings (VTTS) from binary choice data. Fosgerau (2004) deals with the case of just one time component.
Mogens Fosgerau
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

DeepST-Net: Leveraging Spatiotemporal Data Refinement for Enhanced Travel Time Prediction

open access: yesApplied Sciences
Accurate travel time prediction is essential for optimizing transportation systems and alleviating congestion in urban environments. This study introduces a comprehensive framework that combines advanced spatiotemporal data refinement techniques with a ...
Amira Benlecheb   +3 more
doaj   +1 more source

ANALYSING THE HOLIDAY PATTERN AND TRAVEL DEMAND OF REPEAT TRAVELLERS: THE CASE OF PENANG [PDF]

open access: yes
The purpose of this paper is to analyse the travel characteristics as well as tourism attributes that are perceived as important amid repeat travellers in Penang, paying attention on comparison between first time and repeat travellers among international
Saiful Bahri Mohd Kamal, Melinda Yunos
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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