Results 121 to 130 of about 15,987,795 (287)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Travel Time Budget – Decomposition of the Worldwide Mean [PDF]
The paper is concerned with the travel activity and more specifically the urban travel time during a day. This individual mean travel time budget (TTB) has been hypothesised by Zahavi (1980) to be a constant amount of time close to 1 hour per day.
Iragaël Joly
core
Generalization strategies for improving bus travel time prediction across networks
Journal of Urban ManagementThis study focuses on developing and evaluating predictive models for bus travel times adaptable to any transit network, or to new roadway segments without prior travel time data.
Zack Aemmer +3 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Civil Engineering Dimension, 2014 Conventional data collection methods lack real time information and involve excessive cost of installation and maintenance. A real-time, low cost travel time data collection system can be developed using mobile phones.
Satyakumar, M., Anil, R., Sivakumar, B.
doaj
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
The role of travel time budgets – Representation of a demand derived from activity participation [PDF]
The paper exams the relationships between travel and activity times, in 7 travel surveys from 4 French and 3 Swiss cities, observed at two different periods.
Iragaël Joly
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Travel time prediction in public transportation [PDF]
, 2021 ÖZET Günümüzde toplu ulaşımda, ulaşım süresinin tahmini, bilgiye kolayca erişebilen ve günlük aktivitelerini planladıkları gibi yolculuklarını da planlamak isteyen yolcular için oldukça önemlidir. Büyük şehirlerde ulaşım süresi bazı öngörülemeyen dış faktörler nedeniyle çeşitlilik göstermektedir. Bu nedenle bu çalışma, GPS cihazları ile toplanan veriyi
openaire
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source