Results 41 to 50 of about 63,289 (291)

Real-Time Travel Time Prediction Based on Evolving Fuzzy Participatory Learning Model

Journal of Advanced Transportation, 2022
Urban expressways take on rapid and external transport in the city due to their fast, safe, and large capacity. Implementing intelligent and active traffic control can effectively improve the performance of urban traffic and mitigate the urban traffic ...
Yongyi Li, Ming Zhang, Yixing Ding, Zhenghua Zhou, Lingyu Xu   +4 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Freedom, self-prediction, and the possibility of time travel [PDF]

Philosophical Studies, 2018
Do time travellers retain their normal freedom and abilities when they travel back in time? Lewis, Horwich and Sider argue that they do. Time-travelling Tim can kill his young grandfather, his younger self, or whomever else he pleases—and so, it seems can reasonably deliberate about whether to do these things. He might not succeed. But he is still just
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Prediction of open-pit mine truck travel time based on LSTM-TabTransformer

Scientific Reports
Truck travel time prediction is the basis for real-time optimal scheduling decision of open-pit trucks. Most prediction models for open-pit truck travel time mainly rely on a single machine learning algorithm or model to optimize the hyperparameters ...
Jingchang Zhao, Lei Gao, Shihao Ren
doaj   +1 more source

Travel Time in Case of Accident Prediction Model

Procedia - Social and Behavioral Sciences, 2012
AbstractThe aim of this paper is to estimate the travel time along a motorway section, both in undisturbed condition and taking into account a perturbation due to an accident. The estimated travel time is calculated adding the travel time under normal traffic conditions, the time used settling the accident area and the time needed to dissolve the queue.
DOMENICHINI, LORENZO, SALERNO, GIORGIO, FANFANI, FRANCESCO, M. BACCHI, GIACCHERINI, ANDREA, L. COSTALLI, C. BARONCELLI   +6 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Space-Time Hybrid Model for Short-Time Travel Speed Prediction

Discrete Dynamics in Nature and Society, 2018
Short-time traffic speed forecasting is a significant issue for developing Intelligent Transportation Systems applications, and accurate speed forecasting results are necessary inputs for Intelligent Traffic Security Information System (ITSIS) and ...
Qi Fan, Wei Wang, Xiaojian Hu, Xuedong Hua, Zhuyun Liu   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source