Results 61 to 70 of about 63,289 (291)

Prediction error of travel time between stops.

, 2022
Prediction error of travel time between stops.
Les Lauber (11868978), Yuran Pan (11027810), Xinhuan Zhang (9541577), Hongjie Liu (285479), Meili Xie (4569490), Junqing Shi (2033311)   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Steps of travel time prediction between stops.

, 2022
Steps of travel time prediction between stops.
Les Lauber (11868978), Yuran Pan (11027810), Xinhuan Zhang (9541577), Hongjie Liu (285479), Meili Xie (4569490), Junqing Shi (2033311)   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Inland Waterway Travel Time Prediction

, 2022
This report focuses on the portion of the Upper Mississippi River between Mile Marker 338 and Mile Marker 462—a stretch encompassing Locks 16 through 20 in southeast Iowa and northeast Missouri. This part of the river system is an important artery for agricultural shipments.
Kruse, C. James, Monsreal, Mario, Kang, Dong Hun (Don)   +2 more
openaire   +2 more sources

Real-Time Short-Term Travel Time Prediction [PDF]

, 2012
Real-time short-term travel time prediction is a critical component of the Intelligent Transportation System (ITS) and an important element of the Advanced Traveler Information System (ATIS). Accurate and reliable travel time prediction enables both user
Qiao, Wenxin
core  

Probability hypothesis density filtering for real-time traffic state estimation and prediction [PDF]

, 2013
The probability hypothesis density (PHD) methodology is widely used by the research community for the purposes of multiple object tracking. This problem consists in the recursive state estimation of several targets by using the information coming from an
El Faouzi, Nour Eddin, Mihaylova, Lyudmila, Canaud, M., Faouzi, Nour-Eddin El, Sau, Jacques, Canaud, Matthieu, El Faouzi, Nour-Eddin, Mihaylova, L., Sau, J., El Faouzi, N.E.   +9 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Freeway truck travel time prediction for freight planning using truck probe GPS data

European Journal of Transport and Infrastructure Research, 2016
Predicting truck (heavy vehicle) travel time is a principal component of freight project prioritization and planning. However, most existing travel time prediction models are designed for passenger vehicles and fail to make truck specific forecasts or ...
Zun Wang, Anne V. Goodchild, Edward McCormack   +2 more
doaj   +1 more source