Results 81 to 90 of about 15,987,795 (287)

Performance evaluation of an adaptive travel time prediction model [PDF]

open access: yes, 2005
This paper presents a travel time prediction model\ud and evaluates its performance and transferability. Advanced\ud Travelers Information Systems (ATIS) are gaining more and\ud more importance, increasing the need for accurate, timely and\ud useful ...
Kuwahara, Masao   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A knowledge based real-time travel time prediction system for urban network [PDF]

open access: yes, 2010
[[abstract]]Many approaches had been proposed for travel time prediction in these decades; most of them focus on the predicting the travel time on freeway or simple arterial network.
Lee, WH (Lee, Wei-Hsun); Tseng, SS (Tseng, Shian-Shyong); Tsai, SH (Tsai, Sheng-Han)
core  

Comparison of Machine Learning and Statistical Approaches for Predicting Travel Times in the Oklahoma Highway System [PDF]

open access: yes, 2020
Traffic management systems play a vital role in supporting the smooth flow of traffic in road networks. By accurately predicting travel time, a traffic condition parameter that is extensively used in such systems, we can significantly improve the ...
Saidi, Said Jalal
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Time Travel and theories of Time [PDF]

open access: yes, 2000
This paper is a survey of the theories of time travel in a perspective close to theories of time. In the last section we discuss the special ontology of the objects that exist on closed timelike curves.
Muntean, Ioan Lucian
core  

Predicting the travel time of arterial traffic using particle filter with speed matrix

open access: yesMATEC Web of Conferences, 2018
Travel time prediction is an essential part of intelligent transportation system applications. However, the existing travel time prediction methods mainly focus on the freeway due to its simplicity and the high coverage of sensors and few researches have
Yang Qiangrong, Peng Qi
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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