Results 71 to 80 of about 15,987,795 (287)

Benefits and issues of urban network travel time prediction [PDF]

, 2008
This paper presents the benefits and issues related to travel time prediction on urban network. Travel time information quantifies congestion and is perhaps the most important network performance measure. Travel time prediction has been an active area of
Dumont, Andre-Gilles, Bhaskar, Ashish, Chung, Edward   +2 more
core  

Urban Link Travel Time Prediction Based on a Gradient Boosting Method Considering Spatiotemporal Correlations

ISPRS International Journal of Geo-Information, 2016
The prediction of travel times is challenging because of the sparseness of real-time traffic data and the intrinsic uncertainty of travel on congested urban road networks.
Faming Zhang, Xinyan Zhu, Tao Hu, Wei Guo, Chen Chen, Lingjia Liu   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Benefits and issues for bus travel time estimation and prediction [PDF]

, 2012
Bus travel time estimation and prediction are two important modelling approaches which could facilitate transit users in using and transit providers in managing the public transport network.
Kieu, Le Minh, Bhaskar, Ashish, Chung, Edward   +2 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Inland Waterway Travel Time Prediction

, 2022
This report focuses on the portion of the Upper Mississippi River between Mile Marker 338 and Mile Marker 462—a stretch encompassing Locks 16 through 20 in southeast Iowa and northeast Missouri. This part of the river system is an important artery for agricultural shipments.
Kruse, C. James, Monsreal, Mario, Kang, Dong Hun (Don)   +2 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Freeway truck travel time prediction for freight planning using truck probe GPS data

European Journal of Transport and Infrastructure Research, 2016
Predicting truck (heavy vehicle) travel time is a principal component of freight project prioritization and planning. However, most existing travel time prediction models are designed for passenger vehicles and fail to make truck specific forecasts or ...
Zun Wang, Anne V. Goodchild, Edward McCormack   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source