Results 41 to 50 of about 15,823,049 (301)

Impact of connected and automated vehicles on the travel time reliability of an urban network

open access: yesInternational Journal of Transportation Science and Technology
Connected and automated vehicles (CAVs) have the potential to revolutionise the transportation industry, with a plethora of research already revealing considerable gains in safety, travel time and mobility, as well as reduced congestion and pollution. As
Shehani Samaranayake   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

CONSIDERING TRAVEL TIME RELIABILITY AND SAFETY FOR EVALUATION OF CONGESTION RELIEF SCHEMES ON EXPRESSWAY SEGMENTS

open access: yesIATSS Research, 2009
Evaluation of the efficiency of congestion relief schemes on expressways has generally been based on average travel time analysis. However, road authorities are much more interested in knowing the possible impacts of improvement schemes on safety and ...
Babak MEHRAN
doaj   +1 more source

Metro Train Operation Plan Analysis Based on Station Travel Time Reliability

open access: yesJournal of Advanced Transportation, 2021
The train operation plan plays an essential role in metro systems and directly affects transportation organization efficiency and passenger service level.
Ruihua Xu, Fangsheng Wang, Feng Zhou
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Study on the Shortest Reliable Path of Stochastic Time-Dependent Transportation Networks considering Waiting Time at Signalized Intersections

open access: yesJournal of Advanced Transportation, 2023
Theoretical research is conducted on finding the shortest path with stochastic and time-dependent characteristics of link travel time in urban road networks.
Yanming Sun, Jie Li, Shixian Liu
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Degradable transportation network with the addition of electric vehicles: Network equilibrium analysis.

open access: yesPLoS ONE, 2017
Introducing electric vehicles (EVs) into urban transportation network brings higher requirement on travel time reliability and charging reliability. Specifically, it is believed that travel time reliability is a key factor influencing travelers' route ...
Rui Zhang, Enjian Yao, Yang Yang
doaj   +1 more source

Last-Mile Shuttle Planning for Improving Bus Commuters’ Travel Time Reliability: A Case Study of Beijing

open access: yesJournal of Advanced Transportation, 2022
This study proposes a multiobjective mixed integer nonlinear programming model for a last-mile shuttle service to improve bus commuters’ travel time reliability.
Weibin Kou   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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