Results 51 to 60 of about 78,588 (264)

Degradable transportation network with the addition of electric vehicles: Network equilibrium analysis.

PLoS ONE, 2017
Introducing electric vehicles (EVs) into urban transportation network brings higher requirement on travel time reliability and charging reliability. Specifically, it is believed that travel time reliability is a key factor influencing travelers' route ...
Rui Zhang, Enjian Yao, Yang Yang
doaj   +1 more source

Metro Train Operation Plan Analysis Based on Station Travel Time Reliability

Journal of Advanced Transportation, 2021
The train operation plan plays an essential role in metro systems and directly affects transportation organization efficiency and passenger service level.
Ruihua Xu, Fangsheng Wang, Feng Zhou
doaj   +1 more source

Travel Time Reliability in Indiana

, 1969
Travel time and travel time reliability are important performance measures for assessing traffic condition and extent of congestion on a roadway. This study first uses a floating car technique to assess travel time and travel time reliability on a number of Indiana Highways.
Maria Martchouk, Fred Mannering, Lakhwinder Singh   +2 more
openaire   +2 more sources

A Median-Based Misery Index for Travel Time Reliability

Procedia Computer Science, 2023
Travel time reliability is vital for both road agencies and road users. Expected travel time reliability can be used by road agencies to assess the state of a transportation system, and by road users, to schedule their trips. Road network deficiencies, such as insufficient traffic flow capacity of a road segment or poor road design, have a negative ...
Henrik Fredriksson, Johan Holmgren, Mattias Dahl, Benny Lövström   +3 more
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Last-Mile Shuttle Planning for Improving Bus Commuters’ Travel Time Reliability: A Case Study of Beijing

Journal of Advanced Transportation, 2022
This study proposes a multiobjective mixed integer nonlinear programming model for a last-mile shuttle service to improve bus commuters’ travel time reliability.
Weibin Kou, Jiayu Wang, Yanxi Liu, Chenxu Li   +3 more
doaj   +1 more source

Estimation of the Network Reliability for a Stochastic Cold Chain Network with Multi-State Travel Time

Applied Sciences, 2023
A stochastic cold chain (SCC) is a common supply chain in real life that emphasizes the need for commodities to arrive fresh within time constraints. In previous research on supply chains, the time factor was regarded as a fixed number.
Thi-Phuong Nguyen, Chin-Lung Huang, Yi-Kuei Lin   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Uncovering the Influence of Commuters’ Perception on the Reliability Ratio

Findings, 2019
The dominant method for measuring values of travel time savings (VOT) and values of travel time reliability (VOR) is discrete choice modeling. Studies using revealed preference have tended to use travel times measured by devices such as loop detectors ...
Carlos Carrion, David Levinson
doaj   +1 more source