Steps against the burden of Parkinson's disease (StepuP): Protocol of a randomized controlled trial elucidating the biomechanical and neurophysiological mechanisms of a speed dependent treadmill training intervention. [PDF]
van Leeuwen AM +32 more
europepmc +1 more source
Abstract Recent studies have focused on the potential benefits of heat exposure for cardiovascular health. However, the acute effects of heat therapy on conduit arteries remain unclear, particularly in overweight and obese older males and females. This study aimed to compare core temperature (Tc), heart rate (HR), and brachial, femoral, and carotid ...
Juliene G. Costa +6 more
wiley +1 more source
Effects of Adding Treadmill Training to Conventional Physiotherapy on Lower-Limb Thermal Asymmetry, Motor Function, and Walking Capacity in Patients with Chronic Stroke: A Randomized Controlled Trial. [PDF]
Gómez-Mateos M +5 more
europepmc +1 more source
Exercise intolerance and impaired aerobic capacity in heart transplant recipients
Abstract Heart transplant recipients exhibit reduced exercise tolerance and persistently diminished aerobic capacity despite exercise training. Exercise tolerance depends on integrated oxygen transport and utilization, which are impaired in heart transplant recipients.
Fred W. Kolkhorst +2 more
wiley +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Treadmill training induces sex-dependent changes in hippocampal epigenetic patterns and plaque-associated microglial morphology in aged TgF344 rats. [PDF]
Schuller AJ +8 more
europepmc +1 more source
Mitochondrial haplotype and sex modulate responses to endurance exercise training
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn +8 more
wiley +1 more source
A treadmill training program in a gamified virtual reality environment combined with transcranial direct current stimulation in Parkinson's Disease: Preliminary results of a mixed methods randomized controlled trial. [PDF]
Bosch-Barceló P +5 more
europepmc +1 more source
Abstract Figure Legend Endurance‐trained runners completed a 5‐week hot‐water‐immersion (HWI) intervention (≥40°C, 45 min, five sessions per week) and a training‐matched control period in a cross‐over design. HWI induced a 33 g increase in haemoglobin mass (Hbmass) and a 10 mL expansion in left‐ventricular end‐diastolic volume (LVEDV), resulting in a 2.
Elliott J. Jenkins +7 more
wiley +1 more source

