Results 141 to 150 of about 3,567,945 (293)

Accounting for spillover when using the augmented synthetic control method: estimating the effect of localized COVID-19 lockdowns in Chile [PDF]

open access: yesarXiv
The implementation of public health policies, particularly in a single or small set of units (e.g., regions), can create complex dynamics with effects extending beyond the directly treated areas. This paper examines the direct effect of COVID-19 lockdowns in Chile on the comunas where they were enacted and the spillover effect from neighboring comunas.
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Treatment Strategies for Chorioretinal Vascular Diseases: Advantages and Disadvantages of Individualised Therapy

open access: yesEuropean Medical Journal Diabetes, 2016
Chorioretinal vascular diseases are among the leading causes of blindness in industrialised countries. The recent development and widespread adoption of intravitreal pharmacotherapy enables surgeons to not only stabilise disease in most cases, but also ...
Michael W. Stewart
doaj  

One-year outcomes and safety assessment of faricimab in treatment-naïve patients with neovascular age-related macular degeneration in Japan

open access: yesScientific Reports
This multicentre retrospective study evaluated the 1-year outcomes and safety profile of faricimab in treatment-naïve patients with neovascular age-related macular degeneration (nAMD).
Ryo Mukai   +21 more
doaj   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Extending torsors on the punctured Spec(A_inf) [PDF]

open access: yesarXiv, 2018
We prove that torsors under parahoric group schemes on the punctured spectrum of Fontaine's ring $A_{\mathrm{inf}}$, extend to the whole spectrum. Using descent we can extend a similar result for the ring $\mathfrak{S}$ of Kisin and Pappas to full generality. Moreover, we treat similarly the case of equal characteristic.
arxiv  

Estimating Semiparametric Panel Data Models by Marginal Integration [PDF]

open access: yes
We propose a new methodology for estimating semiparametric panel data models, with a primary focus on the nonparametric component. We eliminate individual effects using first differencing transformation and estimate the unknown function by marginal ...
Qian, Junhui, Wang, Le
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

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