Results 131 to 140 of about 192,839 (256)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Real-world outcomes of intravitreal bevacizumab treat-and-extend for cystoid macular oedema secondary to central retinal vein occlusion. [PDF]
Int Ophthalmol, 2023 Gildea D, Tang B, Baily C, Ryan A.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
[Intracranially extended nasopharyngeal angiofibroma treated surgically and by radiotherapy].
Otolaryngologia polska = The Polish otolaryngology, 2004 A case of nasopharyngeal angiofibroma with intracranial extension is presented. The parasellar extension was demonstrated on CT and MRI scans after four operations performed in two centres. The boy was radiated (42 Gy/t). Two and a half years follow up using MRI showed gradual regression of the tumour down to minimal enhancement in the parasellar ...
Anna, Szymańska +4 more
openaire +1 more source
Hypoglycaemic attacks treated by ambulance personnel with extended training. [PDF]
BMJ, 1990 C, Weston, M, Stephens
openaire +4 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Long-term disease control with anti-VEGF treat-and-extend treatment in macular edema due to retinal vein occlusion. [PDF]
BMC OphthalmolFischer S, Hoffmann L, Hatz K.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Multimodal imaging biomarkers associated with recurrence of diabetic macular edema during aflibercept treat-and-extend therapy. [PDF]
Sci RepKim K, Lee J, Choi J, Yu SY.
europepmc +1 more source