Results 31 to 40 of about 18,252,794 (250)

Efficacy of stem cells therapy for Crohn’s fistula: a meta-analysis and systematic review

Stem Cell Research & Therapy, 2021
Background Fistulas have puzzled us all the time and stem cell therapy for it is still in its infancy. We conducted a meta-analysis and systematic review to evaluate the efficacy of stem cells and its potential mechanisms in the management of Crohn’s ...
Yantian Cao, Qi Su, Bangjie Zhang, Fangfang Shen, Shaoshan Li   +4 more
doaj   +1 more source

Drug-related adverse events necessitating treatment discontinuation in pediatric inflammatory bowel disease patients. [PDF]

, 2022
BACKGROUND AND AIMS Inflammatory bowel disease (IBD) requires long-term drug therapy in most patients, posing a risk for adverse drug events with the need for discontinuation.
Spalinger, J., Schibli, S., von Graffenried, Thea, Pittet, Valérie, Valérie Pittet, Braegger, C., Salzmann, M., von Graffenried, T., Christiane Sokollik, Schoepfer, A., Thea von Graffenried, Andreas Nydegger, Salzmann, Medea, Christian Braegger, Braegger, Christian, Alain Schoepfer, Sokollik, Christiane, Franziska Righini-Grunder, Johannes Spalinger, Schibli, Susanne, Nydegger, Andreas, Nydegger, A., Pittet, V., Sokollik, C., Spalinger, Johannes, Susanne Schibli, Righini-Grunder, Franziska, Medea Salzmann, Schoepfer, Alain, Righini-Grunder, F.   +29 more
core   +2 more sources

Clinical diagnosis and treatment recommendations for immune checkpoint inhibitor‐related hematological adverse events

Thoracic Cancer, 2020
Immune checkpoint inhibitors (ICIs) are able to reactivate the immune system, thereby enhancing the anti‐tumor effects. However, over‐activated T cells may induce immune‐related adverse events (irAEs). Hematological irAEs are rarely reported which mainly
Junling Zhuang, Jianhua Du, Xiaoxiao Guo, Jiaxin Zhou, Lian Duan, Wei Qiu, Xiaoyan Si, Li Zhang, Yue Li, Xiaowei Liu, Hanping Wang, Daobin Zhou, Li Zhang   +12 more
doaj   +1 more source

Rare levetiracetam-related adverse events in treatment of epilepsy

Эпилепсия и пароксизмальные состояния
The article systematizes data on rare levetiracetam-related adverse events that go beyond the approved data provided in package insert. The key factor in selecting an antiepileptic drug is the risk-benefit ratio, which is largely determined by the ...
T. V. Melashenko, Z. G. Tadtaeva, A. N. Galustyan, N. A. Galankin, O. A. Gromova, I. S. Sardaryan   +5 more
doaj   +1 more source

Management of immune checkpoint inhibitor‐related rheumatic adverse events

Thoracic Cancer, 2020
Immune checkpoint inhibitors (ICIs), which target the programmed cell death receptor‐1 and cytotoxic T lymphocyte‐associated antigen‐4 signaling pathways, represent remarkable breakthroughs in cancer treatment and have improved survival among patients ...
Jiaxin Zhou, Hanping Wang, Xiaoxiao Guo, Qian Wang, Lian Duan, Xiaoyan Si, Li Zhang, Xiaowei Liu, Yue Li, Wen Zhang, Li Zhang   +10 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Treatment related toxicity in BRCA1-associated epithelial ovarian cancer – is DNA repairing impairment associated with more adverse events? [PDF]

, 2016
Aim of the study: The presence of BRCA germline mutations in patients with ovarian cancer has been shown to have predictive and prognostic significance, including increased platinum-sensitivity.
Elżbieta Nowara, Danuta Starzyczny-Słota, Magdalena Budryk, Agnieszka Badora-Rybicka   +3 more
core   +1 more source

Comparison of immune checkpoint inhibitors related to pulmonary adverse events: a retrospective analysis of clinical studies and network meta-analysis

BMC Medicine
Background Immune checkpoint inhibitors (ICIs) have transformed tumor treatment. However, the risk of pulmonary adverse events (PAEs) associated with ICI combination therapy is still unclear.
Baohui Hong, Bin Du, Rong Chen, Caiyun Zheng, Ruping Ni, Maobai Liu, Jing Yang   +6 more
doaj   +1 more source

An Updated Meta-Analysis for Safety Evaluation of Alirocumab and Evolocumab as PCSK9 Inhibitors

Cardiovascular Therapeutics, 2023
Background. Alirocumab and evolocumab, as protein convertase subtilisin kexin type 9 (PCSK9) inhibitors, have been reported to reduce cardiovascular risk. This meta-analysis is aimed at updating the safety data of PCSK9 inhibitors. Methods.
Hye Duck Choi, Ji Hae Kim
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source